| Enhanced metabolic response to caffeine in exercise-trained human subjects. | |
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MedLine Citation:
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PMID: 3902769 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The effect of caffeine on resting metabolic rate (RMR) was investigated in eight trained and eight nontrained young male subjects. The ingestion of 4 mg/kg caffeine produced a greater increase of RMR in trained subjects. This effect was associated with a greater increase in plasma free fatty acids and a larger fall in respiratory quotient, indicating an enhanced lipid oxidation following caffeine in exercise-trained subjects. An initial fall in plasma glucose was observed but only in trained subjects, and caffeine did not change plasma insulin in either group studied. Caffeine caused a significant fall in plasma norepinephrine and an increase in plasma epinephrine in both groups of subjects, but this action was significantly greater in trained subjects. It is suggested that the greater increase in RMR observed in trained subjects following caffeine ingestion is related to an enhanced lipid mobilization, possibly produced by a greater epinephrine secretion and by subsequent increased lipid oxidation. |
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Authors:
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J LeBlanc; M Jobin; J Côté; P Samson; A Labrie |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of applied physiology (Bethesda, Md. : 1985) Volume: 59 ISSN: 8750-7587 ISO Abbreviation: J. Appl. Physiol. Publication Date: 1985 Sep |
Date Detail:
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Created Date: 1985-12-10 Completed Date: 1985-12-10 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 8502536 Medline TA: J Appl Physiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 832-7 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adipose Tissue
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metabolism Adult Blood Glucose / metabolism Body Weight Caffeine / pharmacology* Epinephrine / blood Fatty Acids, Nonesterified / metabolism Heart Rate / drug effects Humans Insulin / blood Lipid Mobilization / drug effects* Male Oxygen Consumption / drug effects Physical Exertion* |
| Chemical | |
Reg. No./Substance:
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0/Blood Glucose; 0/Fatty Acids, Nonesterified; 11061-68-0/Insulin; 51-43-4/Epinephrine; 58-08-2/Caffeine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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