| Enhanced lipid peroxidation in patients during coronary artery bypass grafting. | |
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MedLine Citation:
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PMID: 8070827 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Lipid peroxidation products were measured at various time intervals in 20 patients with coronary artery disease, who underwent coronary artery bypass graft (CABG) surgery. Post-operative blood lipid peroxides were found to be significantly higher (p < 0.001) than the preoperative value. Lipid peroxides raised to a peak value of 46.42 +/- 12.86 n mol/g Alb at 5 min of reperfusion when compared to the basal value and afterwards the level declined to 41.02 +/- 7.09 at 2 hrs and remained in that level even at 24 hrs of reperfusion. This increase implies an enhancement in free radical mediated oxidation of membrane lipids during bypass surgery and thus provides evidence for free radical generation during myocardial reperfusion. |
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Authors:
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N Jayakumari; K S Kumari; V Ambikakumari; Y Nazer; M P Singh; K G Balakrishnan; K S Iyer |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Indian heart journal Volume: 45 ISSN: 0019-4832 ISO Abbreviation: Indian Heart J Publication Date: 1993 Nov-Dec |
Date Detail:
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Created Date: 1994-09-27 Completed Date: 1994-09-27 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0374675 Medline TA: Indian Heart J Country: INDIA |
Other Details:
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Languages: eng Pagination: 489-91 Citation Subset: IM |
Affiliation:
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Department of Biochemistry, Cardiology and Cardiac Surgery, SCTIMS, Trivandrum. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Coronary Artery Bypass* Coronary Disease / metabolism*, surgery Free Radicals Humans Lipid Peroxidation* Lipid Peroxides / blood Male Middle Aged Myocardial Reperfusion Myocardial Reperfusion Injury / etiology |
| Chemical | |
Reg. No./Substance:
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0/Free Radicals; 0/Lipid Peroxides |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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