| Enhanced intra-aortic balloon pump: markedly improved systemic hemodynamics and cardiac function in canines with severe, acute left ventricular failure. | |
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MedLine Citation:
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PMID: 12139502 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Intra-aortic balloon pumps (IABPs) cannot sustain hemodynamics if the left heart is severely injured. An enhanced IABP was evaluated in 6 anesthetized dogs with acute stenosis of the left anterior descending coronary artery, regional left ventricular (LV) stunning, and global LV dysfunction. An IABP balloon was inserted into the descending aorta and an external chamber containing another IABP balloon was connected to the aorta through a catheter inserted into the left subclavian artery. This emulated the enhanced IABP with a conduit from its external chamber passing axially through an internal IABP balloon. Compared to IABP, enhanced IABP improved hemodynamics and LV function in all conditions. During severe LV dysfunction and circulatory failure, IABP failed to augment diastolic aortic pressure or improve coronary and carotid flows. Enhanced IABP augmented diastolic pressure from 32 +/- 3 mm Hg to 87 +/- 2 mm Hg and increased coronary and carotid flows. Enhanced IABP may be a lifesaving device for patients with severe LV failure. |
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Authors:
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Xiaoming Bian; H Fred Downey |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Artificial organs Volume: 26 ISSN: 0160-564X ISO Abbreviation: Artif Organs Publication Date: 2002 Aug |
Date Detail:
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Created Date: 2002-07-25 Completed Date: 2002-10-16 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7802778 Medline TA: Artif Organs Country: United States |
Other Details:
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Languages: eng Pagination: 727-33 Citation Subset: IM |
Affiliation:
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Department of Integrative Physiology and Cardiovascular Research Institute, University of North Texas Health Science Center at Fort Worth, Fort Worth, Texas 76107-2699, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Analysis of Variance Animals Blood Pressure / physiology Dogs Hemodynamics* Intra-Aortic Balloon Pumping* Ventricular Dysfunction, Left / physiopathology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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