| Enhanced expression of tyrosine hydroxylase and aromatic L-amino acid decarboxylase in cerebellar Purkinje cells of mouse after hyperosmotic stimuli. | |
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MedLine Citation:
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PMID: 7478200 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We examined by immunohistochemistry the effect of salt loading on the expression of tyrosine hydroxylase (TH), aromatic L-amino acid decarboxylase (AADC), and GTP cyclohydrolase I (GCH) in Purkinje cells of the mouse cerebellum. In control mice, only a few Purkinje cells were positive for TH or AADC. No Purkinje cells were stained for GCH. Drinking 2% sodium chloride for 2 weeks resulted in an increase in the number of TH- or AADC-positive Purkinje cells in the caudal vermis, paraflocculus and flocculus of the cerebellum. In contrast, no Purkinje cells were immunoreactive to GCH or L-DOPA after the salt loading. The present findings suggest that the salt loading differentially affects the expression of TH, AADC and GCH in Purkinje cells of the mouse cerebellum. |
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Authors:
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M Sakai; T Fujii; N Karasawa; R Arai; I Nagatsu |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Neuroscience letters Volume: 194 ISSN: 0304-3940 ISO Abbreviation: Neurosci. Lett. Publication Date: 1995 Jul |
Date Detail:
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Created Date: 1995-11-28 Completed Date: 1995-11-28 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7600130 Medline TA: Neurosci Lett Country: IRELAND |
Other Details:
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Languages: eng Pagination: 142-4 Citation Subset: IM |
Affiliation:
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Department of Anatomy, School of Medicine, Fujita Health University, Aichi, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Carboxy-Lyases / genetics* Dehydration Dopamine / metabolism Immunohistochemistry Mice Mice, Inbred Strains Osmosis Purkinje Cells / immunology* Tyrosine 3-Monooxygenase / genetics* |
| Chemical | |
Reg. No./Substance:
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EC 1.14.16.2/Tyrosine 3-Monooxygenase; EC 4.1.1.-/Carboxy-Lyases |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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