Document Detail


Enhanced Enantioselective Recognition with Diastereoisomeric BINOL Based Chiral Fluorescent Boronic Acid Sensors.
MedLine Citation:
PMID:  21637998     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
We prepared the diastereoisomers of BINOL based bisboronic acid chiral probes (the probes are with dual chirogenic centers) for enantioselective recognition of chiral analytes, such as tartaric acids, D-sorbitol, etc. We found the diastereoisomeric probes give different emission intensity-pH profiles, a phenomenon was reported, probably, for the first time. We found that with the second chirogenic center, the selectivity of the probes toward chiral analytes can be improved. For example, the diastereoisomeric probes give drastically different response to D-sorbitol, the same selectivity was not found for the BINOL bisboronic acid probes with single chirogenic center. Our result with the diastereoisomeric probes is helpful for design of new chiral molecular probes to enhance the selectivity of the boronic acid sensors toward chiral analytes.
Authors:
Qiuting Li; Huimin Guo; Yubo Wu; Xin Zhang; Yifan Liu; Jianzhang Zhao
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-6-3
Journal Detail:
Title:  Journal of fluorescence     Volume:  -     ISSN:  1573-4994     ISO Abbreviation:  -     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-6-3     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9201341     Medline TA:  J Fluoresc     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
State Key Laboratory of Fine Chemicals, School of Chemical Engineering, Dalian University of Technology, E-208 Western Campus, 2 Ling-Gong Road, Dalian, 116024, People's Republic of China.
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