Document Detail

Engineering of secondary metabolite pathways.
MedLine Citation:
PMID:  14662388     Owner:  NLM     Status:  MEDLINE    
Nature produces an astonishing wealth of secondary metabolites with important biological functions. To access this diversity of structurally complex chemical compounds for industrial and biomedical applications, cells have been engineered to produce higher levels and/or novel compounds that were previously inaccessible. Recent examples of metabolic and combinatorial engineering illustrate different strategies for the production of secondary metabolites in microbial cells.
Benjamin N Mijts; Claudia Schmidt-Dannert
Related Documents :
20038138 - Mechanistic insight into cell growth, internalization, and cytotoxicity of pamam dendri...
20654408 - Different in vitro systems affect cypia1 activity in response to 2,3,7,8-tetrachlorodib...
21475878 - Intracellular delivery of 2-deoxy-d-glucose into tumor cells by long-term cultivation a...
17503368 - Metabolite antigens and pathway incompatibility.
22139348 - Exocytosis of sh-sy5y single cell with different shapes cultured on ito micro-pore elec...
15180468 - T-cell-targeted biologicals for psoriasis.
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current opinion in biotechnology     Volume:  14     ISSN:  0958-1669     ISO Abbreviation:  Curr. Opin. Biotechnol.     Publication Date:  2003 Dec 
Date Detail:
Created Date:  2003-12-09     Completed Date:  2004-08-26     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9100492     Medline TA:  Curr Opin Biotechnol     Country:  England    
Other Details:
Languages:  eng     Pagination:  597-602     Citation Subset:  IM    
Department of Biochemistry, Molecular Biology & Biophysics, University of Minnesota, 140 Gortner Laboratory, Saint Paul, MN 55108, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Biopolymers / biosynthesis,  chemistry
Carotenoids / biosynthesis,  chemistry
Escherichia coli / genetics,  metabolism
Genetic Engineering*
Models, Biological
Multienzyme Complexes / biosynthesis
Yeasts / genetics,  metabolism
Reg. No./Substance:
0/Biopolymers; 0/Multienzyme Complexes; 36-88-4/Carotenoids

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Protein engineering in bioelectrocatalysis.
Next Document:  Non-canonical amino acids in protein engineering.