Document Detail

Energy expenditure in extremely low birth weight infants near time of hospital discharge.
MedLine Citation:
PMID:  18657827     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To test the hypothesis that total energy expenditure is significantly higher in extremely low birth weight (ELBW) infants compared with healthy term infants near the time of discharge.
STUDY DESIGN: This study was designed to determine total energy expenditure and body composition in a group of ELBW infants nearing discharge receiving full-volume enteral feedings of fortified breast milk or postdischarge formula (Neosure) (n = 10; mean birth weight, 0.8 +/- 0.1 kg; mean gestational age, 26 +/- 0.8 weeks; mean age at study, 68 +/- 9 days; mean postconceptional age, 36 +/- 1 weeks) and compare them with healthy term newborns all receiving breast milk (n = 14; mean birth weight, 3.5 +/- 0.5 kg; mean gestational age, 39.0 +/- 1.4 weeks; mean age at study, 2.3 +/- 1 days). Body composition and total energy expenditure were measured using the doubly labeled water method over a 7-day period.
RESULTS: Mean total energy expenditure was significantly higher in the ELBW infants compared with the term infants (89 +/- 22 kcal/kg/day vs 58 +/- 19 kcal/kg/day; P <or= .001). Total energy expenditure normalized to fat-free mass was also significantly greater in the ELBW infants (98 +/- 3 kcal/kg/day vs 73 +/- 20 kcal/kg/day; P <or= .01).
CONCLUSIONS: The rate of total energy expenditure is greater in ELBW infants nearing discharge compared with normal healthy term infants. In the ELBW infants, higher energy intake compensates for their higher total energy expenditure.
Veronica M Guilfoy; Shirley Wright-Coltart; Catherine A Leitch; Scott C Denne
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't     Date:  2008-07-26
Journal Detail:
Title:  The Journal of pediatrics     Volume:  153     ISSN:  1097-6833     ISO Abbreviation:  J. Pediatr.     Publication Date:  2008 Nov 
Date Detail:
Created Date:  2008-10-22     Completed Date:  2008-11-10     Revised Date:  2014-09-22    
Medline Journal Info:
Nlm Unique ID:  0375410     Medline TA:  J Pediatr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  612-5     Citation Subset:  AIM; IM    
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MeSH Terms
Birth Weight
Body Weight
Case-Control Studies
Energy Intake
Energy Metabolism
Gestational Age
Infant Formula
Infant, Extremely Low Birth Weight / metabolism*,  physiology
Infant, Newborn
Models, Statistical
Oxygen / metabolism
Water / metabolism
Weight Gain
Grant Support
M01 RR000750/RR/NCRR NIH HHS; M01 RR000750-320836/RR/NCRR NIH HHS; MOI-RR-750/RR/NCRR NIH HHS; R01 HD029153/HD/NICHD NIH HHS; R01 HD029153-11/HD/NICHD NIH HHS; R01-HD-29153/HD/NICHD NIH HHS; S10 RR007269/RR/NCRR NIH HHS; S10 RR007269-01/RR/NCRR NIH HHS; S10-RR-07269/RR/NCRR NIH HHS
Reg. No./Substance:
059QF0KO0R/Water; S88TT14065/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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