Document Detail


Energetic behaviour of mitochondria isolated from rat livers perfused with a perfluorodecalin + N,N-perfluorodiethylcyclohexylamine emulsion.
MedLine Citation:
PMID:  2783159     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Rat livers have been perfused with a saline control medium or with a perfluorocarbon emulsion containing perfluorodecalin and N,N-perfluorodiethylcyclohexylamine, and the respiratory rates and transmembrane electrical potentials of mitochondria isolated following perfusion have been evaluated. The results indicate that the perfluorocarbon emulsion used, by providing a good oxygen supply to the perfused liver, allowed to preserve the efficiency of mitochondrial oxidative phosphorylation.
Authors:
D Branca; F Giron; L Conte; E Vincenti; G Scutari
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Publication Detail:
Type:  In Vitro; Journal Article    
Journal Detail:
Title:  Biochemical pharmacology     Volume:  38     ISSN:  0006-2952     ISO Abbreviation:  Biochem. Pharmacol.     Publication Date:  1989 Sep 
Date Detail:
Created Date:  1989-10-16     Completed Date:  1989-10-16     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0101032     Medline TA:  Biochem Pharmacol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  3045-8     Citation Subset:  IM    
Affiliation:
Department of Biological Chemistry, University of Padova, Italy.
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MeSH Terms
Descriptor/Qualifier:
Adenosine Triphosphate / biosynthesis
Animals
Blood Substitutes / pharmacology*
Emulsions
Energy Metabolism / drug effects*
Fluorocarbons / pharmacology*
Mitochondria, Liver / metabolism*
Oxygen Consumption / drug effects
Perfusion
Rats
Chemical
Reg. No./Substance:
0/Blood Substitutes; 0/Emulsions; 0/Fluorocarbons; 306-94-5/perfluorodecalin; 308-95-2/N,N-perfluorodiethylcyclohexylamine; 56-65-5/Adenosine Triphosphate

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