Document Detail


Endurance training: an effective and safe treatment for patients with LGMD2I.
MedLine Citation:
PMID:  17200494     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We studied the effect of aerobic training on conditioning in patients with limb-girdle muscular dystrophy type 2I (LGMD2I). Nine patients with LGMD2I cycled fifty 30-minute sessions at 65% of their maximal oxygen uptake over 12 weeks. Training significantly improved work capacity, paralleled by self-reported improvements. Creatine kinase levels did not increase significantly, and muscle morphology was unaffected. Moderate-intensity endurance training is a safe method to increase exercise performance and daily function in patients with LGMD2I.
Authors:
M-L Sveen; T D Jeppesen; S Hauerslev; T O Krag; J Vissing
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Neurology     Volume:  68     ISSN:  1526-632X     ISO Abbreviation:  Neurology     Publication Date:  2007 Jan 
Date Detail:
Created Date:  2007-01-03     Completed Date:  2007-02-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401060     Medline TA:  Neurology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  59-61     Citation Subset:  AIM; IM    
Affiliation:
Department of Neurology 2082, Rigshospitalet, Blegdamsvej 9, DK-2100 Copenhagen, Denmark. RH18329@rh.hosp.dk
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MeSH Terms
Descriptor/Qualifier:
Adult
Exercise / physiology*
Exercise Therapy / methods*
Female
Humans
Male
Middle Aged
Muscle, Skeletal / pathology,  physiology
Muscular Dystrophies, Limb-Girdle / pathology,  therapy*
Physical Endurance / physiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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