Document Detail

Endtidal carbon dioxide monitoring in children with congenital heart disease during sedation for cardiac catheterization by nonanesthesiologists.
MedLine Citation:
PMID:  17564648     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: This prospective observational study compared endtidal carbon dioxide (P(E)CO(2)) with blood gas carbon dioxide (PaCO(2)) values in children sedated by nonanesthesiologists for cardiac catheterization. METHODS: A nasal cannula designed to obtain gas sampling simultaneously from over the mouth and nares was taped into place after assuring a good waveform. Patients' cardiac lesions, site of blood gas sampling and P(E)CO(2)were recorded. RESULTS: Two hundred and one blood/P(E)CO(2) pairs were measured in 59 patients from 4 days to 18 years of age. Linear regression, Pearson correlation, and Bland-Altman analysis revealed a reasonable relationship (r = 0.493, P < 0.01, bivariate Pearson correlation) for all blood/expired CO(2) pairs even when the blood sample was obtained from an area of the circulation with shunting. There was no significant difference in the accuracy of the blood/P(E)CO(2) pairs between infants who weighed </=15 kg compared with children who weighed >15 kg. Thirteen children were diagnosed with partial or complete airway obstruction. CONCLUSIONS: Endtidal CO(2) measurement provides a reasonable reflection of blood CO(2) values if the expired gas-sampling catheter is taped in place after assuring a good waveform. The veracity of the data was the same throughout the patient size range. Expired CO(2) monitoring is useful for assessing the adequacy of respirations and the patency of the airway in children 3-89 kg.
Charles J Coté; David F Wax; Melissa A Jennings; Carla L Gorski; Kimberly Kurczak-Klippstein
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Paediatric anaesthesia     Volume:  17     ISSN:  1155-5645     ISO Abbreviation:  Paediatr Anaesth     Publication Date:  2007 Jul 
Date Detail:
Created Date:  2007-06-13     Completed Date:  2007-08-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9206575     Medline TA:  Paediatr Anaesth     Country:  France    
Other Details:
Languages:  eng     Pagination:  661-6     Citation Subset:  IM    
Harvard Medical School, Division of Pediatric Anesthesia, Department of Anesthesia and Critical Care Medicine, Massachusetts General Hospital, Boston MA 02114, USA.
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MeSH Terms
Airway Obstruction / metabolism
Blood Gas Analysis
Carbon Dioxide / analysis*,  blood
Child, Preschool
Conscious Sedation*
Heart Catheterization*
Heart Defects, Congenital / blood*
Linear Models
Monitoring, Intraoperative
Reg. No./Substance:
124-38-9/Carbon Dioxide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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