Document Detail

Endovascular treatment of carotid artery stenosis: evidences from randomized controlled trials and actual indications.
MedLine Citation:
PMID:  22567734     Owner:  NLM     Status:  MEDLINE    
Atherosclerotic stenosis of common and internal carotid arteries is a well-recognized risk factor for ischemic stroke, and revascularization has been proven to be the main tool of prevention, particularly for patients with stenosis-related symptoms. While for many years surgical carotid endarterectomy (CEA) has been considered the gold-standard strategy to restore vascular patency, recently the endovascular treatment through percutaneous angioplasty and stent implantation (CAS) has become a valid alternative. In the last years, interesting data about the comparison of these strategies have emerged. CAS seems to cause more peri-procedural strokes, but may also avoid many adverse events related to surgery and general anaesthesia, including peri-procedural myocardial infarction. For these reasons, it was initially considered a second-choice strategy to be adopted in patients for whom surgery was contraindicated. However, more recent trials have shown that CAS might be considered an effective alternative to CEA. Moreover, the rapid evolution of CAS technique and materials suggests its potential to improve outcome and possible superiority compared to CEA in the next future. Purpose of this review is to discuss the most recent clinical evidences concerning the treatment of carotid artery stenosis, with a special focus on the endovascular treatment.
Federica Ilardi; Fabio Magliulo; Giuseppe Gargiulo; Gabriele Giacomo Schiattarella; Giuseppe Carotenuto; Federica Serino; Marco Ferrone; Emanuele Visco; Fernando Scudiero; Andreina Carbone; Cinzia Perrino; Bruno Trimarco; Giovanni Esposito
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace / Fondazione clinica del lavoro, IRCCS [and] Istituto di clinica tisiologica e malattie apparato respiratorio, Università di Napoli, Secondo ateneo     Volume:  76     ISSN:  1122-0643     ISO Abbreviation:  Monaldi Arch Chest Dis     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2012-05-08     Completed Date:  2012-06-19     Revised Date:  2012-06-27    
Medline Journal Info:
Nlm Unique ID:  9307314     Medline TA:  Monaldi Arch Chest Dis     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  183-91     Citation Subset:  IM    
Division of Cardiology, Federico II University of Naples, Italy.
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MeSH Terms
Angioplasty, Balloon, Coronary* / methods
Carotid Stenosis / surgery,  therapy*
Clinical Trials as Topic
Endarterectomy, Carotid*
Patient Selection
Randomized Controlled Trials as Topic
Stroke / prevention & control
Treatment Outcome

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