| Endovascular management of vein of Galen aneurysmal malformations. Influence of the normal venous drainage on the choice of a treatment strategy. | |
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MedLine Citation:
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PMID: 20725731 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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INTRODUCTION: Vein of Galen arteriovenous malformations (VGAM) are rare intracranial vascular lesions mostly involving young children. Endovascular therapy is the current standard of care. Albeit interventional techniques have greatly reduced the once dismal vital and functional prognoses previously associated with these lesions, the treatment of VGAMs remains a complex therapeutic challenge. DISCUSSIONS: This article reviews the available endovascular options for VGAM therapy, emphasizing three points that we have identified as critical in our practice for the establishment of a treatment strategy: (1) the importance of the deep cerebral venous anatomy, in particular the existence of normal drainage through the Galenic system in spite of the VGAM; (2) the concept of treatment staging, for arterial as well as for venous interventions; and (3) the definition of a therapeutic goal that can be attained at a reasonable cost in terms of complication risks and functional outcome. |
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Authors:
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Monica Pearl; Juan Gomez; Lydia Gregg; Philippe Gailloud |
Publication Detail:
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Type: Journal Article; Review Date: 2010-08-20 |
Journal Detail:
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Title: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery Volume: 26 ISSN: 1433-0350 ISO Abbreviation: Childs Nerv Syst Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-09-13 Completed Date: 2010-12-29 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8503227 Medline TA: Childs Nerv Syst Country: Germany |
Other Details:
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Languages: eng Pagination: 1367-79 Citation Subset: IM |
Affiliation:
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Division of Interventional Neuroradiology, The Johns Hopkins Hospital, Baltimore, MD, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Cerebral Angiography Cerebral Veins / pathology, physiopathology* Cerebrovascular Circulation* Child Embolization, Therapeutic / adverse effects, methods* Humans Practice Guidelines as Topic Prognosis Recovery of Function Severity of Illness Index Treatment Outcome Vein of Galen Malformations / physiopathology*, radiography, surgery, therapy* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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