Document Detail


Endovascular management of vein of Galen aneurysmal malformations. Influence of the normal venous drainage on the choice of a treatment strategy.
MedLine Citation:
PMID:  20725731     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
INTRODUCTION: Vein of Galen arteriovenous malformations (VGAM) are rare intracranial vascular lesions mostly involving young children. Endovascular therapy is the current standard of care. Albeit interventional techniques have greatly reduced the once dismal vital and functional prognoses previously associated with these lesions, the treatment of VGAMs remains a complex therapeutic challenge.
DISCUSSIONS: This article reviews the available endovascular options for VGAM therapy, emphasizing three points that we have identified as critical in our practice for the establishment of a treatment strategy: (1) the importance of the deep cerebral venous anatomy, in particular the existence of normal drainage through the Galenic system in spite of the VGAM; (2) the concept of treatment staging, for arterial as well as for venous interventions; and (3) the definition of a therapeutic goal that can be attained at a reasonable cost in terms of complication risks and functional outcome.
Authors:
Monica Pearl; Juan Gomez; Lydia Gregg; Philippe Gailloud
Publication Detail:
Type:  Journal Article; Review     Date:  2010-08-20
Journal Detail:
Title:  Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery     Volume:  26     ISSN:  1433-0350     ISO Abbreviation:  Childs Nerv Syst     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-09-13     Completed Date:  2010-12-29     Revised Date:  2013-05-20    
Medline Journal Info:
Nlm Unique ID:  8503227     Medline TA:  Childs Nerv Syst     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  1367-79     Citation Subset:  IM    
Affiliation:
Division of Interventional Neuroradiology, The Johns Hopkins Hospital, Baltimore, MD, USA.
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MeSH Terms
Descriptor/Qualifier:
Cerebral Angiography
Cerebral Veins / pathology,  physiopathology*
Cerebrovascular Circulation*
Child
Embolization, Therapeutic / adverse effects,  methods*
Humans
Practice Guidelines as Topic
Prognosis
Recovery of Function
Severity of Illness Index
Treatment Outcome
Vein of Galen Malformations / physiopathology*,  radiography,  surgery,  therapy*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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