| Endovascular management of adult coarctation and its complications: intermediate results in a cohort of 22 patients. | |
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MedLine Citation:
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PMID: 19635674 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To determine the safety and effectiveness of current endovascular treatment in adult patients with thoracic aortic coarctation and its complications. METHODS: A cohort of 22 patients was treated for late presenting primary or recurrent coarctation or aneurysmal formation at varying intervals following childhood intervention. RESULTS: Ten patients with recently discovered de novo coarctations were treated with balloon-expandable stents, and an endoluminal graft (ELG) was used in one additional patient. In the other 11 patients with recurrent lesions, three underwent repeat balloon dilation and stenting; eight patients with recurrence with aneurysms received ELGs. The gradients across the coarctation decreased from 49 + 16 to 4 + 7 mmHg (p = 0.001), and the diameters increased from 10 + 4 to 19 + 4mm (p = 0.001). In five of the eight patients (63%) with aneurysms, the ELG covered the subclavian artery, and a carotid subclavian bypass was necessary. Two patients required iliac artery access. No early major complications occurred. At mean follow-up of 31 + 15.6 months, one patient with type II leak resolved spontaneously and another developed neck dilation and type I leak, requiring a second ELG placement. All patients except one had improvements in symptoms and better hypertension control. CONCLUSIONS: We conclude that primary or secondary endovascular intervention in adults with de novo or recurrent coarctation and aneurysms is feasible with good intermediate results. |
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Authors:
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Hani Shennib; Julio Rodriguez-Lopez; Venkatesh Ramaiah; Grayson Wheatley; Jacques Kpodonu; James Williams; Dawn Olson; Edward B Diethrich |
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Publication Detail:
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Type: Evaluation Studies; Journal Article Date: 2009-07-26 |
Journal Detail:
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Title: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery Volume: 37 ISSN: 1873-734X ISO Abbreviation: Eur J Cardiothorac Surg Publication Date: 2010 Feb |
Date Detail:
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Created Date: 2010-02-03 Completed Date: 2011-01-19 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8804069 Medline TA: Eur J Cardiothorac Surg Country: Germany |
Other Details:
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Languages: eng Pagination: 322-7 Citation Subset: IM |
Copyright Information:
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Copyright 2009 European Association for Cardio-Thoracic Surgery. Published by Elsevier B.V. All rights reserved. |
Affiliation:
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Arizona Heart Institute and Hospital, Phoenix, AZ, USA. hanishennib@email.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Angioplasty, Balloon / adverse effects, methods Aorta, Thoracic / abnormalities* Aortic Aneurysm, Thoracic / surgery Aortic Coarctation / radiography, surgery, therapy* Blood Vessel Prosthesis Implantation / methods Epidemiologic Methods Female Humans Male Middle Aged Recurrence Stents Tomography, X-Ray Computed Treatment Outcome Young Adult |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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