| Endovascular treatment for nonacute symptomatic portal venous thrombosis through intrahepatic portosystemic shunt approach. | |
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MedLine Citation:
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PMID: 21106386 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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PURPOSE: To study the safety and efficacy of nonacute symptomatic portal vein thrombosis (PVT) treated by mechanical thrombectomy combined with pharmacologic thrombolysis through an intrahepatic portosystemic shunt (IPS) approach. MATERIALS AND METHODS: Thirteen patients with nonacute symptomatic PVT were included in this study: five women and eight men, with a mean age of 48.9 y. Indications for therapy were variceal bleeding (n = 7) and abdominal pain, distension, or intermittent melena (n = 6). Through an IPS approach, balloon angioplasty, sheath-directed thrombus aspiration, and continuous infusion of urokinase were performed. Clinical follow-up was performed in all patients. RESULTS: An IPS was successfully created in all patients. After therapy, recanalization of all thrombosed main PVs was achieved. A majority of thrombus was removed and lysed. The overall rate of clinical improvement was 92.3%. One patient died of intraperitoneal bleeding the second day after the procedure, and another two patients experienced minor complications after therapy and recovered completely after conservative medical management. During a mean of 14.9 months of follow-up, two patients experienced recurrent variceal bleeding as a result of shunt dysfunction. Hemostasis was achieved after shunt revision. No other complications occurred. CONCLUSIONS: Through an IPS approach, mechanical thrombectomy combined with pharmacologic thrombolysis was possible as a therapeutic option for patients with nonacute symptomatic PVT. |
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Authors:
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Jianjun Luo; Zhiping Yan; Jianhua Wang; Qingxin Liu; Xudong Qu |
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Publication Detail:
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Type: Journal Article Date: 2010-11-24 |
Journal Detail:
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Title: Journal of vascular and interventional radiology : JVIR Volume: 22 ISSN: 1535-7732 ISO Abbreviation: J Vasc Interv Radiol Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2011-01-03 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9203369 Medline TA: J Vasc Interv Radiol Country: United States |
Other Details:
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Languages: eng Pagination: 61-9 Citation Subset: IM |
Copyright Information:
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Copyright © 2011 SIR. Published by Elsevier Inc. All rights reserved. |
Affiliation:
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Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai, China. michealluo@163.com |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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