Document Detail

Endovascular treatment for nonacute symptomatic portal venous thrombosis through intrahepatic portosystemic shunt approach.
MedLine Citation:
PMID:  21106386     Owner:  NLM     Status:  In-Process    
PURPOSE: To study the safety and efficacy of nonacute symptomatic portal vein thrombosis (PVT) treated by mechanical thrombectomy combined with pharmacologic thrombolysis through an intrahepatic portosystemic shunt (IPS) approach.
MATERIALS AND METHODS: Thirteen patients with nonacute symptomatic PVT were included in this study: five women and eight men, with a mean age of 48.9 y. Indications for therapy were variceal bleeding (n = 7) and abdominal pain, distension, or intermittent melena (n = 6). Through an IPS approach, balloon angioplasty, sheath-directed thrombus aspiration, and continuous infusion of urokinase were performed. Clinical follow-up was performed in all patients.
RESULTS: An IPS was successfully created in all patients. After therapy, recanalization of all thrombosed main PVs was achieved. A majority of thrombus was removed and lysed. The overall rate of clinical improvement was 92.3%. One patient died of intraperitoneal bleeding the second day after the procedure, and another two patients experienced minor complications after therapy and recovered completely after conservative medical management. During a mean of 14.9 months of follow-up, two patients experienced recurrent variceal bleeding as a result of shunt dysfunction. Hemostasis was achieved after shunt revision. No other complications occurred.
CONCLUSIONS: Through an IPS approach, mechanical thrombectomy combined with pharmacologic thrombolysis was possible as a therapeutic option for patients with nonacute symptomatic PVT.
Jianjun Luo; Zhiping Yan; Jianhua Wang; Qingxin Liu; Xudong Qu
Related Documents :
1423396 - Morphologic and clinical results of the transjugular intrahepatic portosystemic stent-s...
8362776 - Transcatheter occlusion of patent ductus arteriosus in adults.
12128316 - Management of hydrocephalus associated with occipital encephalocoele using endoscopic t...
6229176 - Adverse reactions to vancomycin used as prophylaxis for csf shunt procedures.
20411376 - Popliteal artery-tibial plateau relationship before and after total knee replacement: a...
517586 - Coagulation studies of patients taking low-dose heparin during and after major gynecolo...
Publication Detail:
Type:  Journal Article     Date:  2010-11-24
Journal Detail:
Title:  Journal of vascular and interventional radiology : JVIR     Volume:  22     ISSN:  1535-7732     ISO Abbreviation:  J Vasc Interv Radiol     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2011-01-03     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9203369     Medline TA:  J Vasc Interv Radiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  61-9     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 SIR. Published by Elsevier Inc. All rights reserved.
Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai, China.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Novel insights into the function of ?-cell M3 muscarinic acetylcholine receptors: therapeutic implic...
Next Document:  Fenestration of aortic stent grafts-in vitro tests using various device combinations.