Document Detail


Endotherapy for pain in chronic pancreatitis.
MedLine Citation:
PMID:  19120857     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Pain is the most distressing symptom of chronic pancreatitis. Although the pathogenesis of pain is still poorly understood, an increase in intraductal pressure may be the dominant factor. The management of pain can involve medical, endoscopic, neurolytic, and surgical therapies. Endotherapy includes pancreatic sphincterotomy, extraction of stones, placement of stent, and dilatation of strictures, sometimes preceded or followed by extracorporeal shock-wave lithotripsy. Several studies have now shown that endotherapy provides partial or complete relief of pancreatic pain in a majority of patients with an acceptable frequency of early and late complications. Endotherapy should now graduate from an experimental form of treatment to a realistic treatment option in patients with chronic or relapsing pain, particularly in the setting of calcific chronic pancreatitis.
Authors:
Sudeep Khanna; Rakesh K Tandon
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of gastroenterology and hepatology     Volume:  23     ISSN:  1440-1746     ISO Abbreviation:  J. Gastroenterol. Hepatol.     Publication Date:  2008 Nov 
Date Detail:
Created Date:  2009-01-05     Completed Date:  2009-04-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8607909     Medline TA:  J Gastroenterol Hepatol     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  1649-56     Citation Subset:  IM    
Affiliation:
Department of Gastroenterology, Pushpawati Singhania Reasearch Institute for Liver, Renal & Digestive Diseases, New Delhi, India.
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MeSH Terms
Descriptor/Qualifier:
Balloon Dilatation
Cholangiopancreatography, Endoscopic Retrograde
Digestive System Surgical Procedures* / adverse effects,  instrumentation
Endoscopy, Digestive System* / adverse effects,  instrumentation
Humans
Lithotripsy
Pain / etiology,  prevention & control*
Pain Measurement
Pancreas / physiopathology,  radiography
Pancreatitis, Chronic / complications,  physiopathology,  radiography,  therapy*
Pressure
Recurrence
Sphincterotomy, Endoscopic
Stents
Tomography, X-Ray Computed
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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