| Endothelin-1 release from atherosclerotic plaque after percutaneous transluminal coronary angioplasty in stable angina pectoris and single-vessel coronary artery disease. | |
| | |
MedLine Citation:
|
PMID: 10569670 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
To assess the effects of percutaneous transluminal coronary angioplasty on endothelin-1 (ET-1) release, we assessed ET-1 concentrations at different sites of the coronary circulation in patients submitted to elective procedures. ET-1 levels immediately downstream from the plaque and ET-1 aortocoronary gradient increased significantly after the procedure, which was related to mechanical wall stress in patients only receiving balloons, but not in those undergoing stent percutaneous transluminal coronary angioplasty. No changes were found in the coronary sinus; these results suggest ET-1 release from the plaque rather than an ischemia/reperfusion-related production from the distal myocardium. |
| | |
Authors:
|
A S Petronio; G Amoroso; U Limbruno; R Baglini; G Paterni; E Pinori; M Ferdeghini; A Balbarini; R De Caterina; M Mariani |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: The American journal of cardiology Volume: 84 ISSN: 0002-9149 ISO Abbreviation: Am. J. Cardiol. Publication Date: 1999 Nov |
Date Detail:
|
Created Date: 1999-11-30 Completed Date: 1999-11-30 Revised Date: 2007-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0207277 Medline TA: Am J Cardiol Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 1085-8, A9 Citation Subset: AIM; IM |
Affiliation:
|
Cardio-thoracic Department, University of Pisa, Italy. a.petronio@mail.ao-pisa.toscana.it |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Angina Pectoris / blood, therapy* Angioplasty, Transluminal, Percutaneous Coronary* Coronary Artery Disease / blood, therapy* Endothelin-1 / blood* Female Humans Male Middle Aged Reference Values Stents |
| Chemical | |
Reg. No./Substance:
|
0/Endothelin-1 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Association of mitral annular calcium and of aortic cuspal calcium with coronary artery disease in o...
Next Document: Safety and efficacy of internal cardioversion of atrial fibrillation in patients with impaired left ...