Document Detail

Endothelial lesions associated with gas bubble disease in fish.
MedLine Citation:
PMID:  2061432     Owner:  NLM     Status:  MEDLINE    
Two groups of healthy chinook salmon (Oncorhynchus tshawytscha) were experimentally exposed to gas supersaturated groundwater. Gross lesions consistent with gas bubble disease (GBD) developed. Vascular lesions associated with intravascular gas bubbles were examined with light and scanning electron microscopy. Dermal blood vessels containing gas bubbles were severely dilated. Additionally, the gas bubbles were spatially associated with endothelial lesions ranging from cellular degeneration to exfoliation. The resulting regions of exposed subendothelial connective tissue were sparsely covered by small unidentified adherent cells and strands of fibrin. In the light of these findings, the similarities in vascular pathology between GBD in fish and decompression disease in man are discussed, particularly with respect to the initiation of haemostatic disorders in both conditions.
D J Speare
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of comparative pathology     Volume:  104     ISSN:  0021-9975     ISO Abbreviation:  J. Comp. Pathol.     Publication Date:  1991 Apr 
Date Detail:
Created Date:  1991-08-08     Completed Date:  1991-08-08     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0102444     Medline TA:  J Comp Pathol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  327-35     Citation Subset:  IM    
Department of Pathology and Microbiology, Atlantic Veterinary College, University of Prince Edward Island, Charlottetown, Canada.
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MeSH Terms
Endothelium / pathology,  ultrastructure
Endothelium, Vascular / pathology*,  ultrastructure
Fish Diseases / etiology,  pathology*
Microscopy, Electron, Scanning
Mouth / blood supply
Myocardium / pathology*,  ultrastructure
Salmon / anatomy & histology*
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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