Document Detail


Endothelial keratoplasty without Descemet's stripping in congenital hereditary endothelial dystrophy.
MedLine Citation:
PMID:  23352381     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
PURPOSE: To compare outcomes of non-Descemet's stripping endothelial keratoplasty (nDSEK) with Descemet's stripping endothelial keratoplasty (DSEK) for the surgical management of congenital hereditary endothelial dystrophy (CHED). METHODS: Patients with CHED who were treated with DSEK or nDSEK were analyzed and compared with respect to graft adhesion, graft clarity, visual acuity, refraction, and complications. RESULTS: A total of 6 patients were included in the series. Of these, 3 (mean age, 5.6 ± 1.52 years; 1 male) underwent DSEK and 3 (mean age, 5.6 ± 0.57 years; 2 males) nDSEK. Preoperative best-corrected visual acuity of patients who underwent DSEK was 1.3 logMAR units compared with 1.13 logMAR units for nDSEK patients. There were no intraoperative complications. During the early postoperative period, 1 patient who had n DSEK had lenticule detachment and was successfully managed by repeat air injection. The average time for resolution of graft edema was 30 days. The postoperative best-corrected visual acuity was 0.13 ± 0 .10 in DSEK patients and 0.13 ± 0 .10 in nDSEK patients (P = 1). Mean refraction was comparable in both groups of patients. CONCLUSIONS: The outcomes of nDSEK were similar to DSEK in CHED in this small series. The specific advantage of nDSEK is the decreased surgical time and intraocular tissue manipulation.
Authors:
Jatin N Ashar; Muralidhar Ramappa; Sunita Chaurasia
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-24
Journal Detail:
Title:  Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus / American Association for Pediatric Ophthalmology and Strabismus     Volume:  -     ISSN:  1528-3933     ISO Abbreviation:  J AAPOS     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9710011     Medline TA:  J AAPOS     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2013 American Association for Pediatric Ophthalmology and Strabismus. Published by Mosby, Inc. All rights reserved.
Affiliation:
Cornea and Anterior Segment Services, L.V. Prasad Eye Institute, Hyderabad, India.
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