| Endothelial dysfunction and nitric oxide enhancing therapy: a new approach to the treatment of heart failure. | |
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MedLine Citation:
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PMID: 15470301 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Despite ethnic differences in heart failure prevalence, risk profiles, and outcomes, no clinical trials have been designed to prospectively examine the mechanisms responsible for these differences. The African-American Heart Failure Trial is the first prospective trial designed to test a novel therapy that enhances endothelial function and nitric oxide bioavailability in African-American patients with advanced heart failure. |
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Authors:
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Anne L Taylor |
Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: Congestive heart failure (Greenwich, Conn.) Volume: 10 ISSN: 1527-5299 ISO Abbreviation: Congest Heart Fail Publication Date: 2004 Sep-Oct |
Date Detail:
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Created Date: 2004-10-07 Completed Date: 2005-02-03 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9714174 Medline TA: Congest Heart Fail Country: United States |
Other Details:
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Languages: eng Pagination: 237-42 Citation Subset: IM |
Affiliation:
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University of Minnesota Medical School,420 Delaware Street S.E., MMC 293, Minneapolis, MN 55455, USA. taylo135@umn.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult African Americans Aged Aged, 80 and over Drug Therapy, Combination Endothelium, Vascular / drug effects*, physiopathology Female Heart Failure / drug therapy*, ethnology, physiopathology Humans Hydralazine / pharmacology, therapeutic use* Isosorbide / pharmacology, therapeutic use* Male Middle Aged Nitric Oxide / physiology* Prospective Studies Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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10102-43-9/Nitric Oxide; 652-67-5/Isosorbide; 86-54-4/Hydralazine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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