Document Detail

Endosulfan and other organochlorine pesticide residues in maternal and cord blood in North Indian population.
MedLine Citation:
PMID:  18488129     Owner:  NLM     Status:  MEDLINE    
Humans are exposed to various environmental chemicals such as organochlorine pesticide residues, heavy metals, polychlorinatedbiphenyls (PCBs) etc. There is paucity of data regarding the present blood levels of organochlorine residues in North Indian population with reference to reproductive health. The present study was designed to analyze the levels of organochlorine pesticide residues in maternal and cord blood samples of normal healthy women with full term pregnancy to gain insight into the current status of pesticide burden in newborns. Hexachlorocyclohexane (HCH) contributed maximum towards the total organochlorine residues present in maternal and cord blood followed by endosulfan, pp' DDE and pp' DDT being the least. This is also the first report indicating endosulfan levels in this population. Our data indicates a transfer rate of 60-70% of these pesticides from mothers to newborns and this high rate of transfer of pesticides is of great concern as it may adversely affect the growth and development of newborn.
Rahul Pathak; Sanvidhan G Suke; Rafat S Ahmed; A K Tripathi; Kiran Guleria; C S Sharma; S D Makhijani; Meenu Mishra; B D Banerjee
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-05-17
Journal Detail:
Title:  Bulletin of environmental contamination and toxicology     Volume:  81     ISSN:  0007-4861     ISO Abbreviation:  Bull Environ Contam Toxicol     Publication Date:  2008 Aug 
Date Detail:
Created Date:  2008-07-03     Completed Date:  2008-12-05     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0046021     Medline TA:  Bull Environ Contam Toxicol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  216-9     Citation Subset:  IM    
Department of Biochemistry, University College of Medical Sciences, Dilshad Garden, Delhi, 110 095, India.
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MeSH Terms
Endosulfan / blood*
Fetal Blood / chemistry*
Infant, Newborn
Insecticides / blood*
Pesticide Residues / blood*
Reg. No./Substance:
0/Insecticides; 0/Pesticide Residues; 115-29-7/Endosulfan

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