Document Detail

[Endoscopy of the larynx by hyperspectral imaging].
MedLine Citation:
PMID:  23202859     Owner:  NLM     Status:  In-Data-Review    
BACKGROUND: Hyperspectral imaging has been proven to be useful in remote earth sensing, e.g., satellite-based classification of vegetation. After modifying it for in vivo evaluation of the larynx using microscopy, we show its adoption for endoscopes.
MATERIALS AND METHODS: In addition to routine microlaryngoscopies under white light inspection, the laryngoscopy was also performed with not only a conventional operation microscope mounted with a tuneable monochromatic light source and a synchronously triggered monochromatic CCD camera (n = 47 patients), but also a similarly modified rigid 0° endoscope (n = 16 patients). Hyperspectral image cubes were obtained between 390 and 680 nm, analyzed using established software tools, and the data using microscope versus endoscope were compared.
RESULTS: Under endoscopy, illumination was more even and sterical resolution appeared unchanged at significantly shorter image acquisition times. Hyperspectral classification delineated areas of altered mucosa without further external information irrespective of whether image cubes were generated with microscopy or endoscopy.
CONCLUSION: Hyperspectral imaging can be transferred not only to micro(laryngo)scopy but also to endoscopy with rigid optics. This opens the way to a variety of clinically relevant anatomical regions (e.g., upper aerodigestive tract). Its adoption to flexible optics will further broaden this spectrum.
A O H Gerstner; W Laffers; G Schade; F Göke; R Martin; B Thies
Publication Detail:
Type:  English Abstract; Journal Article    
Journal Detail:
Title:  HNO     Volume:  60     ISSN:  1433-0458     ISO Abbreviation:  HNO     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-12-03     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2985099R     Medline TA:  HNO     Country:  Germany    
Other Details:
Languages:  ger     Pagination:  1047-52     Citation Subset:  IM    
Klinik und Poliklinik für Hals-Nasen-Ohren-Heilkunde/Chirurgie, Universität Bonn, Sigmund-Freud-Str. 25, 53105, Bonn, Deutschland,
Vernacular Title:
Endoskopie des Larynx mit Hyperspectral Imaging.
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