| Endoscopy and MR enteroclysis: equivalent tools in predicting clinical recurrence in patients with Crohn's disease after ileocolic resection. | |
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MedLine Citation:
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PMID: 19504611 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Ileocolonoscopy poses the gold standard in the evaluation of postoperative recurrence of Crohn's disease (CD) at the site of ileocolonic anastomosis. Magnetic resonance enteroclysis (MRE) on the other hand is a promising technique for small bowel imaging. The aim was to compare MRE and ileocolonoscopy for predicting clinical recurrence in CD patients who have undergone ileocolonic resection. METHODS: We included 29 patients in the study. The median time since index operation was 35 months and between ileocolonoscopy and MRE was 3 days. Patients were followed up for a maximum of 2 years unless clinical recurrence occurred earlier. Endoscopic findings were evaluated on a 5-grade scale (i0-i4), whereas MRE findings on the neoterminal ileum and anastomosis were assessed according to a previously validated 4-grade scale MR score (MR0-MR3). RESULTS: By classifying patients into subgroups of endoscopic severity of postoperative recurrence using as a threshold an endoscopic score of i3, we found that 10% of patients in the i0 to i2 group had a clinical recurrence during the 2-year follow-up period as compared to 52.6% of subjects with i3 to i4 (P = 0.043). The corresponding clinical exacerbation rates in the subgroups based on MRE severity assessment were 12.5% for MR0 to MR1 and 50% for MR2 to MR3 (P = 0.09). CONCLUSIONS: Our data suggest that colonoscopy and MR enteroclysis are of similar value to predict the risk of clinical recurrence in postoperative patients with Crohn's disease. |
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Authors:
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Stavroula Koilakou; Johannes Sailer; Philipp Peloschek; Arnulf Ferlitsch; Harald Vogelsang; Wolfgang Miehsler; Joel Fletcher; Karl Turetschek; Wolfgang Schima; Walter Reinisch |
Publication Detail:
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Type: Clinical Trial; Journal Article |
Journal Detail:
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Title: Inflammatory bowel diseases Volume: 16 ISSN: 1536-4844 ISO Abbreviation: Inflamm. Bowel Dis. Publication Date: 2010 Feb |
Date Detail:
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Created Date: 2010-01-18 Completed Date: 2010-03-30 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9508162 Medline TA: Inflamm Bowel Dis Country: United States |
Other Details:
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Languages: eng Pagination: 198-203 Citation Subset: IM |
Affiliation:
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Department of Internal Medicine III, Division of Gastroenterology, Medical University of Vienna, Austria. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Colon / pathology, surgery Colonoscopy* Crohn Disease / diagnosis*, pathology, surgery Female Humans Kaplan-Meiers Estimate Magnetic Resonance Imaging / methods* Male Middle Aged Predictive Value of Tests Recurrence Sensitivity and Specificity Severity of Illness Index Time Factors Young Adult |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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