| Endoscopic ultrasound and magnetic resonance imaging for re-staging rectal cancer after radiotherapy. | |
| | |
MedLine Citation:
|
PMID: 19938195 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
AIM: To compare the sensitivity and specificity of two imaging techniques, endoscopic ultrasound (EUS) and magnetic resonance imaging (MRI), in patients with rectal cancer after neoadjuvant chemoradiation therapy. And we compared EUS and MRI data with histological findings from surgical specimens. METHODS: Thirty-nine consecutive patients (51.3% Male; mean age: 68.2 +/- 8.9 years) with histologically confirmed distal rectal cancer were examined for staging. All patients underwent EUS and MRI imaging before and after neoadjuvant chemoradiation therapy. RESULTS: After neoadjuvant chemoradiation, EUS and MRI correctly classified 46% (18/39) and 44% (17/39) of patients, respectively, in line with their histological T stage (P > 0.05). These proportions were higher for both techniques when nodal involvement was considered: 69% (27/39) and 62% (24/39). When patients were sorted into T and N subgroups, the diagnostic accuracy of EUS was better than MRI for patients with T0-T2 (44% vs 33%, P > 0.05) and N0 disease (87% vs 52%, P = 0.013). However, MRI was more accurate than EUS in T and N staging for patients with more advanced disease after radiotherapy, though these differences did not reach statistical significance. CONCLUSION: EUS and MRI are accurate imaging techniques for staging rectal cancer. However, after neoadjuvant RT-CT, the role of both methods in the assessment of residual rectal tumors remains uncertain. |
| | |
Authors:
|
Gianni Mezzi; Paolo Giorgio Arcidiacono; Silvia Carrara; Francesco Perri; Maria Chiara Petrone; Francesco De Cobelli; Simone Gusmini; Carlo Staudacher; Alessandro Del Maschio; Pier Alberto Testoni |
Related Documents
:
|
17032175 - Positron emission tomography/computed tomography: diagnostic accuracy in lymphoma. 17036525 - Combining independent studies of diagnostic fluorodeoxyglucose positron-emission tomogr... 9799345 - Fdg-pet scan in potentially operable non-small cell lung cancer: do anatometabolic pet-... 19184245 - The early use of pet-ct alters the management of patients with esophageal cancer. 1589205 - The pitfall of dacryostenosis. 22180795 - Tracing of the bile-chemotactic migration of juvenile clonorchis sinensis in rabbits by... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: World journal of gastroenterology : WJG Volume: 15 ISSN: 1007-9327 ISO Abbreviation: World J. Gastroenterol. Publication Date: 2009 Nov |
Date Detail:
|
Created Date: 2009-11-25 Completed Date: 2010-02-24 Revised Date: 2010-09-28 |
Medline Journal Info:
|
Nlm Unique ID: 100883448 Medline TA: World J Gastroenterol Country: China |
Other Details:
|
Languages: eng Pagination: 5563-7 Citation Subset: IM |
Affiliation:
|
Gastroenterology and Gastrointestinal Endoscopy Unit, IRCCS Vita-Salute University, San Raffaele Scientific Institute, Milan, Italy. mezzi.gianni@hsr.it |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Combined Modality Therapy / methods Endosonography / methods* Female Humans Magnetic Resonance Imaging / methods Male Middle Aged Neoadjuvant Therapy / methods Neoplasm Metastasis Neoplasm Staging / methods* Prognosis Rectal Neoplasms / diagnosis*, radiotherapy, ultrasonography* Reproducibility of Results Tomography, X-Ray Computed / methods |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Analysis of monocyte chemotactic protein-1 gene polymorphism in patients with spontaneous bacterial ...
Next Document: Routine modified D2 lymphadenectomy performance in pT1-T2N0 gastric cancer.