Document Detail

Endoscopic ultrasound features of protein-losing gastropathy with hypertrophic gastric folds.
MedLine Citation:
PMID:  10817179     Owner:  NLM     Status:  MEDLINE    
BACKGROUND AND STUDY AIMS: We aim to clarify the endoscopic ultrasound (EUS) features of protein-losing gastropathy with hypertrophic gastric folds (PLGH), including Ménétrier's disease. PATIENTS AND METHODS: We analyzed the EUS and histologic findings in five patients who underwent both endoscopic ultrasonography and endoscopic resection. RESULTS: Histologically, we diagnosed one patient as having acute gastritis, three patients as having Ménétrier's disease, and the remaining patient as having hypertrophic lymphocytic gastritis (HLG). Helicobacter pylori was recognized in all but one patient. At EUS every patient was found to have giant gastric folds (13 to 20 mm in diameter), resulting from echogenic thickening of the mucosal layer with or without cystic components. Two patients who underwent eradication therapy of H. pylori showed both clinical and morphologic resolution. CONCLUSIONS: Echogenic thickening of the mucosal layer may be a characteristic EUS feature of protein-losing gastropathy with hypertrophic gastric folds, and H. pylori may be one of the causative agents.
K Hizawa; M Kawasaki; T Yao; K Aoyagi; H Suekane; K Kawakubo; M Fujishima
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Endoscopy     Volume:  32     ISSN:  0013-726X     ISO Abbreviation:  Endoscopy     Publication Date:  2000 May 
Date Detail:
Created Date:  2000-07-19     Completed Date:  2000-07-19     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0215166     Medline TA:  Endoscopy     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  394-7     Citation Subset:  IM    
Second Dept. of Internal Medicine, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
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MeSH Terms
Diagnosis, Differential
Gastritis, Hypertrophic / etiology,  pathology,  ultrasonography*
Helicobacter Infections / complications,  pathology,  ultrasonography
Middle Aged
Protein-Losing Enteropathies / etiology,  pathology,  ultrasonography*
Retrospective Studies
Stomach / ultrasonography*

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