Document Detail

Endoscopic treatment of vesicoureteral reflux with polydimethylsiloxane in adult women.
MedLine Citation:
PMID:  15149753     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: Subureteral injection of bulking agents to a refluxing ureteral orifice is an attractive alternative to open repair. We record our experience of the endoscopic subureteral injection of polydimethylsiloxane in women for vesicoureteral reflux (VUR). METHODS: From January 1997 to December 2001, 30 women (mean age 34.9 years) with 43 refluxing ureters underwent endoscopic treatment. The grade of VUR was I, II, III, and IV in 10, 16, 13, and 4 ureters, respectively. The indication for the procedure was VUR with a history of pyelonephritis in women of childbearing age or in whom antibiotic prophylaxis had been unsuccessful. All women underwent voiding cystourethrogram at 3 months and then yearly after the procedures. Follow-up ranged from 12 to 60 months (mean 26.5 months). RESULTS: Reflux was corrected in 34 ureters after a single injection; only 3 ureters needed a 2nd injection. The overall success rate was 86.0%: for grades I, II, III, and IV was 90.0%, 87.5%, 76.9%, and 100% respectively. The mean hospital stay was 1.31 days (range 1-8 days), and no remarkable surgical complications occurred. Most of the patients in whom VUR was cured or improved showed a reduction in laboratory-proven urinary infection rates. CONCLUSIONS: The endoscopic subureteral injection of polydimethylsiloxane in women with vesicoureteral reflux is an effective therapy with no associated morbidity.
Myung-Soo Choo; Bumsik Hong; Young Hwan Ji; Han Chung; Jin Ho Choe; Won Hee Park; Taehan Park; Kyu-Sung Lee
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European urology     Volume:  45     ISSN:  0302-2838     ISO Abbreviation:  Eur. Urol.     Publication Date:  2004 Jun 
Date Detail:
Created Date:  2004-05-19     Completed Date:  2004-09-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7512719     Medline TA:  Eur Urol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  787-9     Citation Subset:  IM    
Department of Urology, University of Ulsan College of Medicine, Asan Medical Center, 388-1 Pungnap-dong, Songpa-gu, Seoul 138-736, Republic of Korea.
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MeSH Terms
Dimethylpolysiloxanes / administration & dosage*
Follow-Up Studies
Injections, Intralesional
Middle Aged
Silicones / administration & dosage*
Vesico-Ureteral Reflux / therapy*
Reg. No./Substance:
0/Dimethylpolysiloxanes; 0/Silicones; 63148-62-9/baysilon

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