| Endoscopic third ventriculostomy in hydrocephalus associated with achondroplasia. | |
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MedLine Citation:
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PMID: 22208325 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Hydrocephalus in patients with achondroplasia is thought to be due to increased dural sinus venous pressure resulting from narrowing of the jugular foramen. In this setting, where hydrocephalus is presumed to be "vascular" in origin and therefore communicating, endoscopic third ventriculostomy (ETV) would seem contraindicated. The authors describe 3 patients in whom ETV was successfully performed, resulting in MR imaging-documented decreases in ventricle size. The patients were 11 months, 33 months, and 13 years at the time of surgery. All patients had serial preoperative MR images demonstrating progressive hydrocephalus in a "triventricular" pattern with a small fourth ventricle but an open aqueduct. All patients had undergone suboccipital decompression for foramen magnum stenosis prior to the treatment of hydrocephalus. Preoperative retrograde venography revealed variable pressure gradients across the jugular foramen. It is postulated that the increase in intracranial venous pressure resulting from jugular foramen stenosis may lead to disproportionate venous engorgement of the cerebellum and some degree of obstructive hydrocephalus amenable to ETV. The authors discuss the role of suboccipital decompression in the progression of hydrocephalus in patients with achondroplasia. |
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Authors:
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Dale Swift; Laszlo Nagy; Brian Robertson |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of neurosurgery. Pediatrics Volume: 9 ISSN: 1933-0715 ISO Abbreviation: J Neurosurg Pediatr Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2012-01-02 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101463759 Medline TA: J Neurosurg Pediatr Country: United States |
Other Details:
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Languages: eng Pagination: 73-81 Citation Subset: IM |
Affiliation:
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Neurosurgeons for Children and. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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