Document Detail


Endoscopic submucosal dissection and preoperative assessment with endoscopic ultrasonography for the treatment of rectal carcinoid tumors.
MedLine Citation:
PMID:  20033710     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Rectal carcinoid tumors 10 mm in diameter or smaller located within the submucosal layer can be cured by local excision including endoscopic treatment. But complete resection of these tumors with endoscopic polypectomy is difficult. This study aimed to evaluate the usefulness of endoscopic submucosal dissection (ESD) and endoscopic ultrasonography (EUS) for the treatment of rectal carcinoid tumors. METHODS: In this study, 22 rectal carcinoid tumors in 21 patients were evaluated with EUS and treated using ESD from January 2004 to December 2008. RESULTS: The mean size of the resected tumors was 6.1 mm (range, 2.0-10 mm) on histopathologic evaluations. When the sizes of the tumors shown by EUS and histopathologic evaluation were compared, the mean values were not significantly different. All the tumors were located within the submucosal layer, and the accuracy of the preoperative depth determination with EUS was 100% (22/22). The mean duration of the ESD procedure was 37 min (range, 20-71 min). The overall rate of en bloc resection with ESD was 100% (22/22). Although postoperative bleeding occurred in two cases (9%), both cases were successfully managed by endoscopic hemostasis. No perforation or recurrence was observed during the mean follow-up period of 30 months (range, 7-66 months). CONCLUSIONS: Endoscopic submucosal dissection and preoperative assessment with EUS are effective for treating rectal carcinoid tumors and enabling en bloc resection.
Authors:
Naoki Ishii; Noriyuki Horiki; Toshiyuki Itoh; Masataka Maruyama; Michitaka Matsuda; Takeshi Setoyama; Shoko Suzuki; Shino Uchida; Masayo Uemura; Yusuke Iizuka; Katsuyuki Fukuda; Koyu Suzuki; Yoshiyuki Fujita
Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2009-12-24
Journal Detail:
Title:  Surgical endoscopy     Volume:  24     ISSN:  1432-2218     ISO Abbreviation:  Surg Endosc     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-05-14     Completed Date:  2010-10-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8806653     Medline TA:  Surg Endosc     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  1413-9     Citation Subset:  IM    
Affiliation:
Department of Gastroenterology, St Luke's International Hospital, 9-1 Akashi-cho, Chuo-ku, Tokyo, Japan. naoishi@luke.or.jp
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Carcinoid Tumor / pathology,  surgery*,  ultrasonography
Colectomy / methods
Dissection / methods*
Endoscopy, Gastrointestinal / methods*
Endosonography / methods*
Female
Follow-Up Studies
Humans
Intestinal Mucosa / pathology,  surgery*,  ultrasonography
Male
Middle Aged
Preoperative Care / methods*
Rectal Neoplasms / pathology,  surgery*,  ultrasonography
Retrospective Studies
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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