Document Detail

Endoscopic results in five patients with Crohn's disease of the esophagus.
MedLine Citation:
PMID:  862576     Owner:  NLM     Status:  MEDLINE    
In our experience with five cases of Crohn's disease of the esophagus, the endoscopic appearance has been demonstrated. Corresponding to the basic pathological changes, the findings are very different, but two stages may be differentiated: Stage I in which inflammatory changes predominate as a mild or more often erosive-ulcerative esophagitis. Stage II is a stenosing form similar to a peptic stenosis or to a stenosing tumor. The morphological changes are predominantly limited to the lower part of the esophagus with a tendency to extend to the proximal regions. The diagnosis may be established endoscopically only in special cases with shallow ulcerations within a normal mucosa or with cobble-stone relief which is usually seen in the colon. In all other cases, a specific macroscopical appearance of Crohn's disease of the esophagus does not exist and no specific differentiation is possible from other forms of esophagitis. Only by a combination of endoscopy, radiology and histology can the diagnosis be suspected. Guided biopsies are not able to confirm the diagnosis histologically. The exact diagnosis of Crohn's disease of the esophagus is only possible by histological examination of the resected esophagus.
H Huchzermeyer; F Paul; E Seifert; H Fröhlich; C W Rasmussen
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Endoscopy     Volume:  8     ISSN:  0013-726X     ISO Abbreviation:  Endoscopy     Publication Date:  1977 May 
Date Detail:
Created Date:  1977-07-29     Completed Date:  1977-07-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0215166     Medline TA:  Endoscopy     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  75-81     Citation Subset:  IM    
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MeSH Terms
Carcinoma, Squamous Cell / pathology
Crohn Disease / diagnosis*,  pathology
Deglutition Disorders / diagnosis
Esophageal Neoplasms / pathology
Esophageal Stenosis / pathology
Esophagitis / diagnosis*,  pathology
Esophagoscopy / methods*
Esophagus / pathology
Middle Aged

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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