Document Detail


Endoscopic resection of juvenile angiofibromas--long term results.
MedLine Citation:
PMID:  16405273     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To evaluate the long term outcome after endoscopic endonasal resection of juvenile nasopharyngeal angiofibromas (JNA). METHODS: Retrospective study of a series of 21 consecutive patients undergoing endoscopic resection of JNA (type I - IIIa according to Fisch) at two Hospital Centers between 1993 and 2002. Mean follow-up was 51.7 months (range 5-120). Extension to the medial aspect of infratemporal fossa and retromaxillary space was no contraindication against an endonasal endoscopic approach. In three cases of type IIIa tumours a computer assisted intraoperative guiding system was applied (ENTrak, GE Medical, Lawrence, USA). RESULTS: Fifteen patients (71.4%) were free of disease after one endoscopic resection. Three patients (14.3%) had an unmistakable recurrence with the need for further treatment at 6, 14, and 23 months, respectively. Two of the three recurrent tumours have been successfully resected endoscopically, one case was treated with gamma knife. In three patients (14.3%) postoperative MRI showed localized enhanced signal, presumably minimal persistent tumour tissue. Without further treatment all of these patients remained free of symptoms and MRI follow up showed no tumour growth over three, five and ten years, respectively. No postoperative long term sequela was observed. CONCLUSIONS: Resection of nasopharyngeal angiofibromas type I-IIIa can be safely achieved endoscopically. The advantage of this minimally invasive technique is avoidance of external scars and low morbidity. The intraoperative computer assisted guiding system ENTrak was highly accurate and provided substantial help in selected cases.
Authors:
Thiemo Hofmann; Manuel Bernal-Sprekelsen; Wolfgang Koele; Pia Reittner; Erich Klein; Heinz Stammberger
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Publication Detail:
Type:  Journal Article; Multicenter Study    
Journal Detail:
Title:  Rhinology     Volume:  43     ISSN:  0300-0729     ISO Abbreviation:  Rhinology     Publication Date:  2005 Dec 
Date Detail:
Created Date:  2006-01-12     Completed Date:  2006-03-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0347242     Medline TA:  Rhinology     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  282-9     Citation Subset:  IM    
Affiliation:
Department of ORL Head & Neck Surgery, Medical University of Graz, Austria. thiemo.hofmann@meduni-graz.at
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Angiofibroma / pathology,  surgery*
Angiography
Embolization, Therapeutic
Endoscopy / methods*
Humans
Male
Nasopharyngeal Neoplasms / pathology,  surgery*
Recurrence
Retrospective Studies
Surgery, Computer-Assisted
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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