Document Detail


Endoscopic removal of large colorectal polyps: prevention of unnecessary surgery?
MedLine Citation:
PMID:  12626909     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: Because of the potential risk of malignancy and technical difficulties in achieving complete removal, large colorectal polyps represent a special problem for the endoscopist. The aim of this study was to evaluate the capabilities and risks of endoscopy in complete removal of large colorectal polyps. METHODS: Endoscopic polypectomy of 186 colorectal polyps larger than 3 cm in diameter (range, 3-13 cm) was performed; 141 were sessile and 45 pedunculated. Most of the polyps were located in the rectum (n = 88), sigmoid (n = 63), and cecum (n = 9). The remaining adenomas were situated in other parts of the colon. Sessile polyps were removed using the piecemeal technique. RESULTS: Histology results showed an adenoma in 167 cases, and invasive carcinoma was present in the adenoma in 19 patients. Of the adenomas, 29 were tubulous, 118 tubulovillous, and 20 villous; adenoma with severe dysplasia was found in 49 cases. Complete endoscopic removal was achieved in all sessile and pedunculated polyps. None of the patients with invasive carcinoma who underwent surgical resection (n = 10) had any evidence of tumor in the resected specimen. Bleeding occurred in 4 patients after polypectomy (2 percent). Perforation occurred in 1 patient (0.5 percent), who had an invasive carcinoma of the cecum. There was no procedure-related mortality. During a mean follow-up period of 40 (range, 3-87) months, 6 patients presented with recurrence of a benign adenoma (3 percent), which was treated endoscopically, and 1 patient presented with a recurrent invasive carcinoma, which was treated surgically. CONCLUSIONS: Endoscopic polypectomy is a safe and effective method of treating large colorectal polyps.
Authors:
J Marek Doniec; Mathias S Löhnert; Bodo Schniewind; Frank Bokelmann; Bernd Kremer; Horst Grimm
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Diseases of the colon and rectum     Volume:  46     ISSN:  0012-3706     ISO Abbreviation:  Dis. Colon Rectum     Publication Date:  2003 Mar 
Date Detail:
Created Date:  2003-03-10     Completed Date:  2003-04-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372764     Medline TA:  Dis Colon Rectum     Country:  United States    
Other Details:
Languages:  eng     Pagination:  340-8     Citation Subset:  IM    
Affiliation:
Department of General and Thoracic Surgery, University Hospital, Christian Albrechts University, Arnold-Heller-Strasse 7, 24105 Kiel, Germany.
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MeSH Terms
Descriptor/Qualifier:
Adenocarcinoma / pathology,  surgery*
Adenomatous Polyps / pathology,  surgery*
Adult
Aged
Aged, 80 and over
Colectomy / utilization*
Colonic Polyps / pathology,  surgery
Colonoscopy / adverse effects,  methods*
Female
Humans
Intestinal Polyps / pathology,  surgery*
Intestine, Large
Male
Neoplasm Recurrence, Local*
Postoperative Hemorrhage
Unnecessary Procedures*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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