Document Detail

Endoscopic mucosal resection for colonic non-polypoid neoplasms.
MedLine Citation:
PMID:  16181365     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Colonic neoplastic lesions can be classified morphologically into polypoid and non-polypoid types. Non-polypoid lesions have a higher malignant potential than polypoid lesions. Removing these lesions and obtaining integral specimen for histopathology evaluation during colonoscopy examination is an important task. Endoscopic mucosal resection (EMR) is an alternative to surgery for removing of non-polypoid lesions of the GI tract. This study assessed the safety, efficacy, and clinical outcomes of EMR. PATIENTS AND METHODS: From October 2000 to October 2003 during the routine colonoscopy performed at one medical center, identified 152 non-polypoid colonic neoplasms in 149 patients (92 males, 57 females) were found. The mean patient age was 57.8 +/- 15.5 yr (range 32-80 yr). EMR was performed for lesions suspected of being neoplastic tumors via magnification colonoscopy with the indigo carmine dye spray method. The lesions were removed via EMR with pure cutting current after which hemoclips were applied to the resected wounds. RESULTS: The study identified 40 flat type lesions, 106 lateral spreading tumors, and 6 depressed lesions that were completely resected. The mean size of lesions was 19.4 +/- 10.3 mm (range 6-60 mm). Histological findings were 4 adenocarcinomas, 59 with high-grade adenoma/dysplasia, and 89 with low-grade adenoma/dysplasia. Two patients experienced bleeding immediately following EMR, while adequate hemostasis was achieved using hemoclips. Neither delayed bleeding nor perforation developed following EMR. CONCLUSION: EMR by using pure cutting current and hemoclip is a useful method for obtaining integral specimen for accurate pathologic assessment. This method provides a safe and minimally invasive technique managing of colonic non-polypoid lesions.
Ming-Yao Su; Chen-Ming Hsu; Yu-Pin Ho; Jau-Min Lien; Chun-Jung Lin; Chang-Tang Chiu; Pang-Chi Chen; Shui-Yi Tung; Cheng-Shyong Wu
Related Documents :
25000705 - Multiorgan fungal infection caused by microsporum canis in a green iguana (iguana iguana).
21957885 - Eyelid myokymia: not always benign.
11288215 - Late presentation of bochdalek hernia: clinical and radiological aspects.
21299625 - Ascending aortopulmonary fistula 40 years after previous cardiac surgery.
6600555 - Scintigraphy of benign exostoses and exostotic chondrosarcomas.
23649075 - Dentigerous cyst with an impacted third molar obliterating complete maxillary sinus.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of gastroenterology     Volume:  100     ISSN:  0002-9270     ISO Abbreviation:  Am. J. Gastroenterol.     Publication Date:  2005 Oct 
Date Detail:
Created Date:  2005-09-26     Completed Date:  2005-11-10     Revised Date:  2006-06-06    
Medline Journal Info:
Nlm Unique ID:  0421030     Medline TA:  Am J Gastroenterol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2174-9     Citation Subset:  IM    
Digestive Therapeutic Endoscopic Center, Department of Gastroenterology, Chang-Gung Memorial Hospital, Linkou Medical Center, Chang-Gung University, Taiwan, ROC.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Adenoma / pathology,  surgery*
Aged, 80 and over
Colonic Neoplasms / pathology,  surgery*
Colonoscopy / methods*
Follow-Up Studies
Hemostasis, Surgical / instrumentation*
Intestinal Mucosa / pathology,  surgery*
Middle Aged
Retrospective Studies
Treatment Outcome
Comment In:
Am J Gastroenterol. 2006 May;101(5):1155; author reply 1155-6   [PMID:  16696792 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  The role of high-magnification-chromoscopic colonoscopy in hereditary nonpolyposis colorectal cancer...
Next Document:  Risk factors for hepatitis C on the Texas-Mexico border.