Document Detail


Endoscopic manometry of the sphincter of Oddi in patients with Lemmel's syndrome.
MedLine Citation:
PMID:  9548305     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Endoscopic manometry was performed to evaluate the motor activity of the sphincter of Oddi (OS) in six patients with Lemmel's syndrome, four of whom had acute cholangitis and two of whom had acute pancreatitis. As controls, 24 patients undergoing cholecystectomy without juxtapapillary duodenal diverticula (JPD) for cholelithiasis or cholesterol polyps in the gallbladder were also studied. The OS basal pressure and contraction pressure values were 12.4 +/- 5.1 mmHg and 103.4 +/- 24.3 mmHg, respectively, in the patients with Lemmel's syndrome, and 19.5 +/- 5.1 mmHg and 136.8 +/- 28.2 mmHg, respectively, in the control patients. These differences between the groups were statistically significant; however, the wave frequency was not significantly different between the groups. The mean percentages of antegrade, simultaneous, and retrograde sequences were 37.5% +/- 11.3%, 19.9% +/- 8.7%, and 43.4% +/- 11.7%, respectively, in the patients with Lemmel's syndrome, and 66.5% +/- 11.0%, 20.2% +/- 4.7%, and 14.3% +/- 9.2%, respectively, in the controls. The differences between the groups were significant (P < 0.01) for the antegrade and retrograde sequences. These findings indicate that dysfunction of the OS in patients with Lemmel's syndrome could be important in the development of hepatocholangiopancreatic disease caused by duodenobiliary and duodenopancreatic reflux.
Authors:
R Tomita; K Tanjoh
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Surgery today     Volume:  28     ISSN:  0941-1291     ISO Abbreviation:  Surg. Today     Publication Date:  1998  
Date Detail:
Created Date:  1998-05-26     Completed Date:  1998-05-26     Revised Date:  2006-08-03    
Medline Journal Info:
Nlm Unique ID:  9204360     Medline TA:  Surg Today     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  258-61     Citation Subset:  IM    
Affiliation:
First Department of Surgery, Nihon University School of Medicine, Tokyo, Japan.
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Aged
Cholangitis / complications
Cholecystectomy
Cholelithiasis
Cholestasis / complications,  physiopathology*
Endoscopy, Digestive System
Female
Gallbladder Diseases / etiology
Humans
Liver Diseases / etiology
Male
Manometry / methods*
Middle Aged
Motor Activity
Pancreatic Diseases / etiology
Pancreatitis / complications
Sphincter of Oddi / physiopathology*
Syndrome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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