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Endoscopic findings of 100 early-stage esophageal cancers.
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MedLine Citation:
PMID:  18493347     Owner:  NLM     Status:  In-Data-Review    
The morphologic analysis of 100 early squamous cell carcinomas of the esophagus has shown that the barely visible or invisible forms (erythroplakias and occult forms) are predominant. This explains the poor yield of upper gastrointestinal (GI) endoscopies in detecting early cancers, at least in Western countries. Leucoerythroplakias correspond to the most advanced form of early cancers (submucosal invasion in approximately 38% of cases). Pure erythroplakias and occult forms correspond to in situ or intramucosal cancers in over 90% of the cases.Accurate endoscopic staging is possible using morphologic criteria, superficial spread, and rigidity of the wall as parameters. In a prospective study, we show that the degree of accuracy of this staging system reaches 95% for an experienced endoscopist.T(1a)N(0) cancers can benefit from an endoscopic treatment (mucosectomy or photodynamic therapy), because the risk of lymph node metastasis is low (6%). In T(1b)N(0) cancers, the best treatment option is an esophageal resection with extensive mediastinal lymph node dissection for good surgical candidates; PDT combined with adjuvant radiotherapy is a reasonable option for inoperable patients.
P Monnier; C Fontolliet; J B Ollyo
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Diagnostic and therapeutic endoscopy     Volume:  1     ISSN:  1070-3608     ISO Abbreviation:  Diagn Ther Endosc     Publication Date:  1994  
Date Detail:
Created Date:  2008-05-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9502019     Medline TA:  Diagn Ther Endosc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  83-92     Citation Subset:  -    
Otolaryngology Head & Neck Surgery CH-1011CHUV Lausanne Switzerland.
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Journal Information
Journal ID (nlm-ta): Diagn Ther Endosc
ISSN: 1070-3608
ISSN: 1029-0516
Publisher: Hindawi Publishing Corporation
Article Information
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Copyright ? 1994 Hindawi Publishing Corporation.
open-access: This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Received Day: 27 Month: 1 Year: 1994
Accepted Day: 4 Month: 4 Year: 1994
Print publication date: Year: 1994
Volume: 1 Issue: 2
First Page: 83 Last Page: 92
ID: 2362472
PubMed Id: 18493347
Publisher Item Identifier: S1070360894000172
DOI: 10.1155/DTE.1.83

Endoscopic Findings of 100 Early-Stage Esophageal Cancers
Ph. Monnier1
Ch. Fontolliet2
J. B. Ollyo3
1OtolaryngologyHead & Neck SurgeryCH-1011CHUVLausanneSwitzerland
2Institute of PathologyUNILLausanneSwitzerland

Article Categories:
  • Research Article

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