Document Detail

Endoscopic diagnosis of early Barrett's neoplasia: Perspectives for advanced endoscopic technology.
MedLine Citation:
PMID:  24754238     Owner:  NLM     Status:  In-Data-Review    
Barrett's esophagus (BE) is a metaplastic condition that occurs secondary to gastroesophageal reflux disease. BE is also a precursor to esophageal adenocarcinoma, which, although still rare in Japan, is one of the most rapidly increasing cancers in Western countries. However, the prevalence of gastroesophageal reflux disease has increased significantly over the past few decades in Japan, possibly leading to an incremental rise in BE and the associated inherent risk of adenocarcinoma. Given the poor prognosis of advanced-stage Barrett's adenocarcinoma, endoscopic surveillance is recommended for subjects with BE to detect early neoplasias including dysplasia. However, endoscopic identification of dysplastic lesions is still not sufficiently reliable or subjective, making targeted therapy extremely difficult. Over the past few years, improvements in image resolution, image processing software, and optical filter technology have enabled identification of dysplasia and early cancer in BE patients. We retrieved as many studies on advanced endoscopic technologies in BE as possible from MEDLINE and PubMed. The present review focuses on the emergent clinically available technologies to provide an overview of the technologies, their practical applicability, current status, and future challenges.
Kenichi Goda; Tomohiro Kato; Hisao Tajiri
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society     Volume:  26     ISSN:  1443-1661     ISO Abbreviation:  Dig Endosc     Publication Date:  2014 May 
Date Detail:
Created Date:  2014-04-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9101419     Medline TA:  Dig Endosc     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  311-21     Citation Subset:  IM    
Copyright Information:
© 2014 The Authors. Digestive Endoscopy © 2014 Japan Gastroenterological Endoscopy Society.
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