| Endoscopic components separation for abdominal compartment syndrome. | |
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MedLine Citation:
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PMID: 12885610 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Sustained intraabdominal pressures of 14 to 20 mm Hg have significant pathophysiological consequences, but there is currently no satisfactory low-morbidity procedure appropriate for intervention early in the disease process of abdominal compartment syndrome (ACS). The anatomical principles of abdominal wall components separation were used to develop a percutaneous procedure that increased abdominal capacity and decreased abdominal pressure. METHODS: Using a porcine model, we determined abdominal capacity changes by helium insufflation. Corn oil was then used to create an episode of sustained intraabdominal hypertension and changes in intraabdominal pressure and intestinal mucosal oxygenation were determined. RESULTS: Endoscopic abdominal wall components separation (EACS) increased abdominal capacity by 1 L (from 0.89 +/- 0.39 L to 1.95 +/- 0.48 L; P <0.001). During intraabdominal hypertension, EACS decreased abdominal pressure by 31.6% (from 15.9 +/- 2.1 to 11.0 +/- 1.5 mm Hg; P <0.001). Intestinal PO(2) was increased by 61% (18.8 +/- 11.4 to 30.3 +/- 11.7; P = 0.012) CONCLUSIONS: A minimally invasive procedure (EACS) is feasible and has demonstrated effectiveness in a porcine model of ACS. |
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Authors:
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Miranda Voss; Jose Pinheiro; James Reynolds; Rebecca Greene; Mark Dewhirst; Steven N Vaslef; Erik Clary; W Steve Eubanks |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: American journal of surgery Volume: 186 ISSN: 0002-9610 ISO Abbreviation: Am. J. Surg. Publication Date: 2003 Aug |
Date Detail:
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Created Date: 2003-07-29 Completed Date: 2003-08-18 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370473 Medline TA: Am J Surg Country: United States |
Other Details:
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Languages: eng Pagination: 158-63 Citation Subset: AIM; IM |
Affiliation:
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Division of Surgery, Box 3479, Duke University Medical Center, Durham, NC 27707, USA. mvoss@duke.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Abdominal Wall Animals Compartment Syndromes / physiopathology, surgery* Endoscopy* Insufflation Intestinal Mucosa / metabolism Oxygen / metabolism Pressure Swine |
| Chemical | |
Reg. No./Substance:
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7782-44-7/Oxygen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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