Document Detail


Endoscopic capsule placement improves the completion rate of small-bowel capsule endoscopy and increases diagnostic yield.
MedLine Citation:
PMID:  20304397     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: The methods for increasing the rate of complete small-bowel examinations by capsule endoscopy (CE) demonstrate conflicting results, and it is unknown whether improving the completion rate of CE transit is correlated with improvement in diagnostic yield. OBJECTIVE: The aim of this study was to determine whether a higher rate of complete small-bowel examinations results in a higher diagnostic yield of CE. DESIGN: Case-control comparison. SETTING: Tertiary care university hospital. PATIENTS: A total of 273 patients underwent conventional CE (group A), and 261 patients underwent real-time CE (group B). Furthermore, the patients in groups A and B were divided into 2 subgroups by pyloric transit time (A1, A2 and B1, B2, respectively). INTERVENTIONS: After swallowing the capsule, each patient was monitored with a real-time viewer in group B, and the patients underwent endoscopic placement if the capsule was delayed in the esophagus or stomach. MAIN OUTCOME MEASUREMENTS: Pyloric transit time, small-bowel transit time, the rate of complete small-bowel examinations, and the diagnostic yield. RESULTS: The rate of complete small-bowel examinations was significantly higher in group B than in group A (87.4% vs 78.0%, respectively; P = .004). The diagnostic yield was significantly higher in group B2 than in group A2 (60.0% vs 41.7%, respectively; P = .019). LIMITATIONS: Nonrandomized study. CONCLUSIONS: Endoscopic placement improves the rate of complete small-bowel examinations, resulting in a higher diagnostic yield of CE.
Authors:
Yun Jie Gao; Zhi Zheng Ge; Hai Ying Chen; Xiao Bo Li; Jun Dai; Chen An Ye; Shu Dong Xiao
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Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2010-03-20
Journal Detail:
Title:  Gastrointestinal endoscopy     Volume:  72     ISSN:  1097-6779     ISO Abbreviation:  Gastrointest. Endosc.     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-07-12     Completed Date:  2010-11-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0010505     Medline TA:  Gastrointest Endosc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  103-8     Citation Subset:  IM    
Copyright Information:
Copyright 2010 American Society for Gastrointestinal Endoscopy. Published by Mosby, Inc. All rights reserved.
Affiliation:
Department of Gastroenterology, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai Institute of Digestive Disease, Shanghai, People's Republic of China.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Capsule Endoscopy / methods*
Case-Control Studies
Diagnosis, Computer-Assisted / instrumentation*
Endoscopy, Gastrointestinal*
Equipment Design
Female
Gastrointestinal Transit*
Humans
Image Interpretation, Computer-Assisted / instrumentation*
Intestinal Diseases / diagnosis*
Intestine, Small*
Male
Middle Aged
Sensitivity and Specificity
Time and Motion Studies
Comments/Corrections
Comment In:
Gastrointest Endosc. 2010 Jul;72(1):109-11   [PMID:  20620277 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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