Document Detail

Endoscopic capsule placement improves the completion rate of small-bowel capsule endoscopy and increases diagnostic yield.
MedLine Citation:
PMID:  20304397     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The methods for increasing the rate of complete small-bowel examinations by capsule endoscopy (CE) demonstrate conflicting results, and it is unknown whether improving the completion rate of CE transit is correlated with improvement in diagnostic yield. OBJECTIVE: The aim of this study was to determine whether a higher rate of complete small-bowel examinations results in a higher diagnostic yield of CE. DESIGN: Case-control comparison. SETTING: Tertiary care university hospital. PATIENTS: A total of 273 patients underwent conventional CE (group A), and 261 patients underwent real-time CE (group B). Furthermore, the patients in groups A and B were divided into 2 subgroups by pyloric transit time (A1, A2 and B1, B2, respectively). INTERVENTIONS: After swallowing the capsule, each patient was monitored with a real-time viewer in group B, and the patients underwent endoscopic placement if the capsule was delayed in the esophagus or stomach. MAIN OUTCOME MEASUREMENTS: Pyloric transit time, small-bowel transit time, the rate of complete small-bowel examinations, and the diagnostic yield. RESULTS: The rate of complete small-bowel examinations was significantly higher in group B than in group A (87.4% vs 78.0%, respectively; P = .004). The diagnostic yield was significantly higher in group B2 than in group A2 (60.0% vs 41.7%, respectively; P = .019). LIMITATIONS: Nonrandomized study. CONCLUSIONS: Endoscopic placement improves the rate of complete small-bowel examinations, resulting in a higher diagnostic yield of CE.
Yun Jie Gao; Zhi Zheng Ge; Hai Ying Chen; Xiao Bo Li; Jun Dai; Chen An Ye; Shu Dong Xiao
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Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2010-03-20
Journal Detail:
Title:  Gastrointestinal endoscopy     Volume:  72     ISSN:  1097-6779     ISO Abbreviation:  Gastrointest. Endosc.     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-07-12     Completed Date:  2010-11-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0010505     Medline TA:  Gastrointest Endosc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  103-8     Citation Subset:  IM    
Copyright Information:
Copyright 2010 American Society for Gastrointestinal Endoscopy. Published by Mosby, Inc. All rights reserved.
Department of Gastroenterology, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai Institute of Digestive Disease, Shanghai, People's Republic of China.
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MeSH Terms
Capsule Endoscopy / methods*
Case-Control Studies
Diagnosis, Computer-Assisted / instrumentation*
Endoscopy, Gastrointestinal*
Equipment Design
Gastrointestinal Transit*
Image Interpretation, Computer-Assisted / instrumentation*
Intestinal Diseases / diagnosis*
Intestine, Small*
Middle Aged
Sensitivity and Specificity
Time and Motion Studies
Comment In:
Gastrointest Endosc. 2010 Jul;72(1):109-11   [PMID:  20620277 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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