Document Detail

Endoscopic laser thyroarytenoid myoneurectomy in patients with adductor spasmodic dysphonia: a pilot study on long-term outcome on voice quality.
MedLine Citation:
PMID:  21940146     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: Adductor spasmodic dysphonia (ADSD) is a focal laryngeal dystonia, which compromises greatly the quality of life of the patients involved. It is a severe vocal disorder characterized by spasms of laryngeal muscles during speech, producing phonatory breaks, forced, strained and strangled voice. Its symptoms result from involuntary and intermittent contractions of thyroarytenoid muscle during speech, which causes vocal fold to strain, pressing each vocal fold against the other and increasing glottic resistance. Botulinum toxin injection remains the gold-standard treatment. However, as injections should be repeated periodically leading to voice quality instability, a more definitive procedure would be desirable. In this pilot study we report the long-term vocal quality results of endoscopic laser thyroarytenoid myoneurectomy.
STUDY DESIGN: Prospective study.
METHODS: Surgery was performed in 15 patients (11 females and four males), aged between 29 and 73 years, diagnosed with ADSD. Voice Handicap Index (VHI) was obtained before and after surgery (median 31 months postoperatively).
RESULTS: A significant improvement in VHI was observed after surgery, as compared with baseline values (P=0.001). The median and interquartile range for preoperative VHI was 99 and 13, respectively and 24 and 42, for postoperative VHI. Subjective improvement of voice as assessed by the patients showed median improvement of 80%.
CONCLUSIONS: Because long-term follow-up showed significant improvement of voice quality, this innovative surgical technique seems a satisfactory alternative treatment of ADSD patients who seek a definite improvement of their condition.
Domingos Hiroshi Tsuji; Marystella Tomoe Takahashi; Rui Imamura; Adriana Hachiya; Luiz Ubirajara Sennes
Related Documents :
25174536 - Arthroscopically assisted shoulder arthrodesis: is it an effective technique?
22157136 - The natural course of infantile spinal muscular atrophy with respiratory distress type ...
25459036 - Outcomes after transfemoral transcatheter aortic valve replacement: a comparison of the...
25354746 - The number of valves requiring surgery does not affect early and late survival in redo ...
22847896 - The advance male sling as a minimally invasive treatment for intrinsic sphincter defici...
20065366 - Thrombosis markers in hip versus knee arthroplasty: a pilot study.
Publication Detail:
Type:  Journal Article     Date:  2011-09-22
Journal Detail:
Title:  Journal of voice : official journal of the Voice Foundation     Volume:  26     ISSN:  1873-4588     ISO Abbreviation:  J Voice     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-09-07     Completed Date:  2013-02-14     Revised Date:  2013-05-02    
Medline Journal Info:
Nlm Unique ID:  8712262     Medline TA:  J Voice     Country:  United States    
Other Details:
Languages:  eng     Pagination:  666.e7-12     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 The Voice Foundation. Published by Mosby, Inc. All rights reserved.
Department of Otorhinolaryngology, University of São Paulo, School of Medicine, São Paulo, SP, Brazil.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Disability Evaluation
Dysphonia / diagnosis,  physiopathology,  surgery*
Laryngeal Muscles / innervation,  physiopathology,  surgery*
Laryngoscopy* / instrumentation
Laser Therapy* / instrumentation
Lasers, Gas
Middle Aged
Muscle Denervation* / instrumentation
Pilot Projects
Prospective Studies
Recovery of Function
Recurrent Laryngeal Nerve / physiopathology,  surgery*
Speech Production Measurement
Time Factors
Treatment Outcome
Voice Quality*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Vocal impact of a prolonged reading task at two intensity levels: objective measurements and subject...
Next Document:  Comparison of Semiquantitative and Quantitative Assessment of Severity of Aortic Regurgitation: Clin...