Document Detail

Endoneural vessel involvement in hypothyroidism.
MedLine Citation:
PMID:  3623878     Owner:  NLM     Status:  MEDLINE    
Light-microscope findings and pathological ultrastructural changes in sural nerve biopsies from two patients affected by hypothyroidism, one with overt signs of peripheral neuropathy, the other asymptomatic, were studied. In both patients the endoneural vessels showed clear pathological changes similar to those of other metabolic neuropathies, but more marked in the symptomatic patient. It is proposed that the changes observed in the nerve fibers in hypothyroid neuropathy are secondary to changes in the endothelial cells and in the vessel wall.
G Cavaletti; M Guazzi; A Marcucci; A Miani; M G Petruccioli; G Pizzini; G Tredici; M Viecca
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Italian journal of neurological sciences     Volume:  8     ISSN:  0392-0461     ISO Abbreviation:  Ital J Neurol Sci     Publication Date:  1987 Jun 
Date Detail:
Created Date:  1987-10-22     Completed Date:  1987-10-22     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8006502     Medline TA:  Ital J Neurol Sci     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  259-64     Citation Subset:  IM    
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MeSH Terms
Blood Vessels / pathology,  ultrastructure
Hypothyroidism / pathology*
Middle Aged
Nerve Fibers, Myelinated / pathology
Spinal Nerves / blood supply*
Sural Nerve / blood supply*,  pathology,  ultrastructure

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