Document Detail


Endonasal venular permeability in rats exposed to the cold.
MedLine Citation:
PMID:  948976     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Sixteen rats were killed 22 hrs after being injected with a dose of 4 mCi(198)Au mixed with 16 mg of inert colloidal gold/100g body wt. The anterior nasal mucosa of the septum and turbinates in 10 rats which were injected and kept in a temperature of 5-7 degrees C showed mean radioactive counts 2-3 times higher than those recorded in the same areas in 6 control rats kept in ordinary room temperature (22 degrees C). In all sixteen rats the highest counts were obtained in the RES organs, namely the liver, spleen, adrenals and the bone marrow, in descending order. Other tissues revealed no significant radioactivity except for minor counts in the lungs and kidneys. The importance of these findings regarding the localisation of granulomatous diseases and vasculitis in the nose is discussed.
Authors:
M W Kanan; P van Diest
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta oto-laryngologica     Volume:  82     ISSN:  0001-6489     ISO Abbreviation:  Acta Otolaryngol.     Publication Date:    1976 Jul-Aug
Date Detail:
Created Date:  1976-10-01     Completed Date:  1976-10-01     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0370354     Medline TA:  Acta Otolaryngol     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  118-22     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Cold Temperature*
Gold Colloid, Radioactive / administration & dosage,  analysis*
Injections, Intravenous
Male
Nasal Mucosa / analysis*
Nasal Septum / analysis
Rats
Chemical
Reg. No./Substance:
0/Gold Colloid, Radioactive

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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