Document Detail


Endomyocardial biopsy in children with Kawasaki disease.
MedLine Citation:
PMID:  2516398     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To study the histopathology of the myocardium in Kawasaki Disease (KD) with various coronary angiographic findings, right endomyocardial biopsy specimens were evaluated on 20 boys and 16 girls with this disorder. KD with coronary artery lesions (CAL) showed various histopathological abnormalities, such as myocellular hypertrophy in 44%, degeneration in 61%, interstitial fibrosis in 44% and endomyocardial changes in 22%. KD without CAL revealed myocellular hypertrophy in 44%, degeneration in 50%, disarray in 28% and interstitial fibrosis in 6%. As in patients with long-standing KD, more than three years after onset, myocardial changes such as myocellular hypertrophy, disarray and interstitial fibrosis persisted, it is suggested that cardiomyopathy may develop in some patients with KD.
Authors:
S Yonesaka; T Nakada; Y Sunagawa; K Tomimoto; S Naka; T Takahashi; T Matubara; I Sekigami
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta paediatrica Japonica; Overseas edition     Volume:  31     ISSN:  0374-5600     ISO Abbreviation:  Acta Paediatr Jpn     Publication Date:  1989 Dec 
Date Detail:
Created Date:  1990-03-16     Completed Date:  1990-03-16     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370357     Medline TA:  Acta Paediatr Jpn     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  706-11     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Cell Nucleus / pathology
Coronary Disease / pathology*
Female
Fibrosis
Humans
Hypertrophy
Male
Mucocutaneous Lymph Node Syndrome / pathology*
Myocardium / pathology*

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