| Endomicroscopy for assessing mucosal healing in patients with ulcerative colitis. | |
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MedLine Citation:
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PMID: 22187709 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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The assessment of tissue healing has emerged as an important treatment goal in patients with inflammatory bowel disease. In patients with ulcerative colitis (UC), mucosal healing may represent the ultimate therapeutic goal due to the fact that the inflammation is limited to the mucosal layer. Mucosal and histological healing may indicate a subset of UC patients in long-term clinical, endoscopic and histological remission in whom immunomodulators, biologics, and even aminosalicylates may be withdrawn. Confocal laser endomicroscopy allows the assessment of residual cellular inflammation, crypt and vessel architecture distortion during ongoing endoscopy, and therefore permits a real-time evaluation of histological healing in patients with ulcerative proctitis. Images of conventional optical microscopy and confocal laser endomicroscopy in patients with ulcerative proctitis in remission are presented. |
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Authors:
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Cristian Gheorghe; Bogdan Cotruta; Razvan Iacob; Gabriel Becheanu; Mona Dumbrava; Liana Gheorghe |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of gastrointestinal and liver diseases : JGLD Volume: 20 ISSN: 1842-1121 ISO Abbreviation: J Gastrointestin Liver Dis Publication Date: 2011 Dec |
Date Detail:
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Created Date: 2011-12-21 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101272825 Medline TA: J Gastrointestin Liver Dis Country: Romania |
Other Details:
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Languages: eng Pagination: 423-6 Citation Subset: IM |
Affiliation:
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Center for Digestive Diseases and Liver Transplantation, Fundeni Clinical Institute, Bucharest, Romania; Email: drgheorghe@xnet.ro. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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