Document Detail


Endomicroscopy for assessing mucosal healing in patients with ulcerative colitis.
MedLine Citation:
PMID:  22187709     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
The assessment of tissue healing has emerged as an important treatment goal in patients with inflammatory bowel disease. In patients with ulcerative colitis (UC), mucosal healing may represent the ultimate therapeutic goal due to the fact that the inflammation is limited to the mucosal layer. Mucosal and histological healing may indicate a subset of UC patients in long-term clinical, endoscopic and histological remission in whom immunomodulators, biologics, and even aminosalicylates may be withdrawn. Confocal laser endomicroscopy allows the assessment of residual cellular inflammation, crypt and vessel architecture distortion during ongoing endoscopy, and therefore permits a real-time evaluation of histological healing in patients with ulcerative proctitis. Images of conventional optical microscopy and confocal laser endomicroscopy in patients with ulcerative proctitis in remission are presented.
Authors:
Cristian Gheorghe; Bogdan Cotruta; Razvan Iacob; Gabriel Becheanu; Mona Dumbrava; Liana Gheorghe
Related Documents :
22142749 - Jaccoud's arthropathy.
22498759 - Reduced perfusion in pulmonary infiltrates of high-risk hematologic patients is a possi...
10823539 - Incidence of septic complications and multiple organ failure in severely injured patien...
17609849 - Head injuries due to landmines.
12352479 - The importance of fracture pattern in guiding therapeutic decision-making in patients w...
6481829 - Emergency bay thoracotomy.
20927139 - Structure of the human gastric bacterial community in relation to helicobacter pylori s...
19729219 - Reduced serum hepcidin levels in patients with chronic hepatitis c.
18583839 - Is aluminum related bone disease common in hemodialysis units using aluminum based phos...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of gastrointestinal and liver diseases : JGLD     Volume:  20     ISSN:  1842-1121     ISO Abbreviation:  J Gastrointestin Liver Dis     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-12-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101272825     Medline TA:  J Gastrointestin Liver Dis     Country:  Romania    
Other Details:
Languages:  eng     Pagination:  423-6     Citation Subset:  IM    
Affiliation:
Center for Digestive Diseases and Liver Transplantation, Fundeni Clinical Institute, Bucharest, Romania; Email: drgheorghe@xnet.ro.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Combined cardiac surgery and liver transplantation: three decades of worldwide results.
Next Document:  Small cell carcinoma: an unusual location in a young healthy female.