| Endometriosis in Italy: From cost estimates to new medical treatment. | |
| | |
MedLine Citation:
|
PMID: 19639499 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Endometriosis is defined as the presence of endometrial-like tissue outside the uterus, which induced a chronic inflammatory reaction. The data collected from Italy showed that around 3 million women are affected by endoemtriosis and the condition was predominantly found in women of reproductive age (50% of women were in the 29-39 age range), only 25% of women were asymptomatic. The associated symptoms can create an impact in general physical, mental, and social well-being. Endometriosis is associated with severe dysmenorrhea, deep dyspareunia, chronic pelvic pain, ovulation pain, cyclical, or perimenstrual symptoms, with or without abnormal bleeding, infertility, and chronic fatigue. The annual cost for hospital admission can be estimated to be in a total around 54 million euros. The average time for right diagnosis is around 9 years still today and it follows a long and expensive diagnostic search. Therapies can be useful to relieve and sometimes solve the symptoms, encourage fertility, eliminate endometrial lesions, and restore the anatomy of the pelvis. For medical therapy, several different preparations (oral contraceptives, progestogenics, gestrinone, danazol, and GnRHa) and new options (GnRH antagonists, aromatase inhibitors, estrogen receptor beta agoinist, progesterone receptor modulators, angiogenesis inhibitors, and COX-2 selective inhibitors) are available. |
| | |
Authors:
|
Stefano Luisi; Lucia Lazzeri; Valentina Ciani; Felice Petraglia |
Related Documents
:
|
16616749 - Fathers over 40 and increased failure to conceive: the lessons of in vitro fertilizatio... 7533699 - Leuprorelin. a review of its pharmacology and therapeutic use in prostatic cancer, endo... 12284659 - Hysterosalpingography versus laparoscopy in infertile women. 17449539 - Interaction between cytochrome p450 gene polymorphisms and serum organochlorine teq lev... 16478589 - Relationship between epidemiological features and aetiology of male infertility as diag... 19389829 - The progesterone receptor coactivator hic-5 is involved in the pathophysiology of endom... 15692239 - Gene-gene and gene-environment interactions in mild hyperhomocysteinemia. 11778069 - Autologous blood transfusion in the united states: clinical and nonclinical determinant... 11089789 - Herpes simplex virus type 2 in prisoners, new south wales, australia. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2009-7-28 |
Journal Detail:
|
Title: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology Volume: - ISSN: 1473-0766 ISO Abbreviation: Gynecol. Endocrinol. Publication Date: 2009 Jul |
Date Detail:
|
Created Date: 2009-7-29 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8807913 Medline TA: Gynecol Endocrinol Country: - |
Other Details:
|
Languages: ENG Pagination: 1-7 Citation Subset: - |
Affiliation:
|
Division of Obstetrics and Gynecology, Department of Pediatrics, Siena, Italy. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Estrogen receptor beta gene polymorphisms and susceptibility to uterine fibroids.
Next Document: Association of polycystic ovary syndrome with cardiovascular risk factors.