Document Detail

Endometriosis and assisted reproduction techniques.
MedLine Citation:
PMID:  20840274     Owner:  NLM     Status:  MEDLINE    
Endometriosis-associated infertility is poorly treatable with various forms of surgery. Therefore, assisted reproduction techniques (ARTs), such as controlled ovarian hyperstimulation, intrauterine insemination, or in vitro fertilization, are commonly used for endometriosis-associated infertility. Endometriosis impairs the efficacy of in vitro fertilization. There is no evidence that ovulation suppression before ART would enhance the efficacy of ART. Resection of minimal/mild endometriosis and/or restoration of the normality of pelvic anatomy may enhance the efficacy of ART, but aggressive ovarian surgery should be avoided, because it reduces the ovarian reserves and the likelihood of pregnancy after ART. The outcome of ART pregnancy is not affected by the history of endometriosis, but the presence of endometrioma may predispose to preterm birth or fetal growth retardation in ART-induced pregnancies. As a whole, infertility due to endometriosis is best treated with various forms of ART, and the earlier clinicians apply these techniques, the more likely pregnancy may ensue.
Päivi Härkki; Aila Tiitinen; Olavi Ylikorkala
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Annals of the New York Academy of Sciences     Volume:  1205     ISSN:  1749-6632     ISO Abbreviation:  Ann. N. Y. Acad. Sci.     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-09-15     Completed Date:  2010-09-28     Revised Date:  2010-10-19    
Medline Journal Info:
Nlm Unique ID:  7506858     Medline TA:  Ann N Y Acad Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  207-13     Citation Subset:  IM    
Copyright Information:
© 2010 New York Academy of Sciences.
Department of Obstetrics and Gynecology, Helsinki University Central Hospital, Helsinki, Finland.
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MeSH Terms
Endometriosis / complications,  therapy*
Gynecologic Surgical Procedures
Infertility, Female / etiology,  therapy*
Ovarian Diseases / complications,  therapy*
Ovulation Inhibition / physiology
Peritoneal Diseases / complications,  therapy*
Reproductive Techniques, Assisted*

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