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Endometrial stromal sarcoma: A review of the literature.
MedLine Citation:
PMID:  22754201     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Endometrial stromal sarcomas are rare malignant tumors of the uterus, and most of the information available in literature is based on small series or case reports. A proper preoperative diagnosis is difficult and in most cases the diagnosis is confirmed after hysterectomy for a presumed benign disease. Endometrial sampling, ultrasound, and magnetic resonance imaging can provide diagnostic clues. Total hysterectomy with bilateral salpingo-oopherectomy is the main line of management and for early disease complete cure is a reality. Ovarian conservation may be possible in young women with early stage disease and the role of lymphadenectomy is controversial. Adjuvant hormone therapy in the form of progesterone, gonadotropin releasing hormone analogues, and aromatase inhibitors are found to be effective in preventing recurrences. Hormone therapy, radiotherapy and surgical excision of the metastasis are recommended for recurrences.
Authors:
Geetha Puliyath; M Krishnan Nair
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Indian journal of medical and paediatric oncology : official journal of Indian Society of Medical & Paediatric Oncology     Volume:  33     ISSN:  0975-2129     ISO Abbreviation:  Indian J Med Paediatr Oncol     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-07-03     Completed Date:  2012-10-02     Revised Date:  2013-05-30    
Medline Journal Info:
Nlm Unique ID:  9604571     Medline TA:  Indian J Med Paediatr Oncol     Country:  India    
Other Details:
Languages:  eng     Pagination:  1-6     Citation Subset:  -    
Affiliation:
Department of Obstetrics and Gynaecology, SUT Academy of Medical Sciences, Trivandrum, Kerala, India.
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