| Endometrial scratching to improve pregnancy rate in couples with unexplained subfertility: A randomized controlled trial. | |
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MedLine Citation:
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PMID: 23106834 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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AIM: The aim of this study was to examine the effect of endometrial scratching in women with unexplained infertility. MATERIAL AND METHODS: A randomized controlled trial was conducted in Mansoura University Teaching Hospital and a private practice setting. A total of 105 couples with unexplained infertility were randomly allocated into two groups: group A comprised 54 women who underwent endometrial scratching in the luteal phase of a spontaneous menstrual cycle; and group B included 51 women who underwent a placebo procedure. The main outcome measured was cumulative clinical pregnancy rate after 6 months and miscarriage rate. RESULTS: Clinical pregnancy rate was significantly higher in the women experiencing endometrial biopsy than in the control group (25.9% and 9.8%, respectively, P = 0.04). There was no significant difference in miscarriage rate between pregnant women in the endometrial injury group and pregnant women in the control group (12.5% and 16.5%, respectively, P = 0.79). CONCLUSIONS: Endometrial scratching may improve clinical pregnancy rates in couples with unexplained infertility. Adequately powered studies are mandated to confirm or refute the findings. |
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Authors:
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Ahmed Gibreel; Ahmed Badawy; Waleed El-Refai; Noha El-Adawi |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-10-29 |
Journal Detail:
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Title: The journal of obstetrics and gynaecology research Volume: - ISSN: 1447-0756 ISO Abbreviation: J. Obstet. Gynaecol. Res. Publication Date: 2012 Oct |
Date Detail:
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Created Date: 2012-10-30 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9612761 Medline TA: J Obstet Gynaecol Res Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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© 2012 The Authors. Journal of Obstetrics and Gynaecology Research © 2012 Japan Society of Obstetrics and Gynecology. |
Affiliation:
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Department of Obstetrics and Gynecology, Mansoura University, Mansoura, Egypt. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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