Document Detail


Endometrial morphology of women using a d-norgestrel-releasing intrauterine device.
MedLine Citation:
PMID:  648644     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Endometrial biopsies were obtained from 12 volunteers treated with d-norgestrel-releasing intrauterine devices (IUDs) with two different release rate. Four subjects scheduled for hysterectomy had d-norgestrel-releasing IUDs inserted approximately 1 month prior to surgery. The effect of d-norgestrel on the endometrium and fallopian tubes of the removed uteri was examined. A uniform suppression of the endometrium with glandular atrophy and decidualization of the stroma was found in all of the endometrial specimens. Moreover, changes similar to those observed during the luteal phase and early pregnancy could be seen in the tubal epithelium.
Authors:
C G Nilsson; T Luukkainen; H Arko
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Fertility and sterility     Volume:  29     ISSN:  0015-0282     ISO Abbreviation:  Fertil. Steril.     Publication Date:  1978 Apr 
Date Detail:
Created Date:  1978-07-24     Completed Date:  1978-07-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  397-401     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Endometrium / anatomy & histology,  drug effects*
Fallopian Tubes / anatomy & histology
Female
Humans
Intrauterine Devices*
Intrauterine Devices, Medicated*
Menstruation
Middle Aged
Norgestrel / administration & dosage,  blood,  pharmacology*
Chemical
Reg. No./Substance:
6533-00-2/Norgestrel

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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