Document Detail


Endometrial inadequacy after treatment with human menopausal gonadotropin/human chorionic gonadotropin.
MedLine Citation:
PMID:  2123159     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The incidence of abnormal endometrial histology in patients undergoing human menopausal gonadotropin/human chorionic gonadotropin (hMG/hCG) treatment during cycles of in vitro fertilization (IVF) or gamete intrafallopian transfer has been reported to be 52% to 91%. The incidence of endometrial inadequacy, as judged by a single late luteal endometrial biopsy, has not been studied in hMG/hCG non-IVF cycles. In the current study, 30 patients (30 cycles) undergoing hMG/hCG treatment were evaluated by an endometrial biopsy. The incidence of endometrial inadequacy was found to be 27%. No preovulatory predictors for endometrial inadequacy could be identified. Therefore, luteal support for patients undergoing non-IVF hMG/hCG cycles should be considered.
Authors:
E Reshef; J H Segars; G A Hill; D D Pridham; M A Yussman; A C Wentz
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Fertility and sterility     Volume:  54     ISSN:  0015-0282     ISO Abbreviation:  Fertil. Steril.     Publication Date:  1990 Dec 
Date Detail:
Created Date:  1991-01-09     Completed Date:  1991-01-09     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1012-6     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, University of Louisville School of Medicine, Kentucky.
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MeSH Terms
Descriptor/Qualifier:
Adult
Biopsy
Chorionic Gonadotropin / adverse effects*,  therapeutic use
Endometrium / drug effects,  pathology*
Estradiol / metabolism
Female
Humans
Luteal Phase
Menotropins / adverse effects*,  therapeutic use
Menstrual Cycle / drug effects
Ovarian Follicle / metabolism
Reference Values
Chemical
Reg. No./Substance:
0/Chorionic Gonadotropin; 50-28-2/Estradiol; 61489-71-2/Menotropins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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