| Endometrial histopathology, ovarian changes and bleeding patterns among users of long-acting progestin-only contraceptives in Egypt. | |
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MedLine Citation:
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PMID: 23113539 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Objective To evaluate endometrial and ovarian effects, and bleeding patterns, among users of Depo-Provera((®)), Norplant((®)), and Implanon((®)). Study design One-hundred and fifty women, who had been using one of these long-acting progestin-only contraceptives (LAPCs) for at least the previous six months, with fifty in each of the groups, were assessed. Results All results are mentioned in the following sequence: (1) Depo-Provera((®)), (2) Norplant((®)), and (3) Implanon((®)). Normal bleeding was reported by 0%, 52%, and 8%; amenorrhoea or infrequent bleeding by 68%, 24%, and 72%; and abnormal bleeding by 32%, 24%, and 20%, respectively (p < 0.001). Histological evaluation revealed an atrophic endometrium in 84%, 32%, and 28%, respectively (p < 0.0001); a progestin effect in 16%, 28%, and 62%, respectively (p < 0.0001), and a proliferative pattern in 0%, 40%, and 10%, respectively (p < 0.0001). Endometrial thickness was 3 ± 0.41 mm, 3.62 ± 0.65 mm, and 5.2 ± 0.84 mm, respectively (p < 0.0001). Follicular growth in the ovaries was observed at ultrasound in 12%, 40%, and 72%, respectively (p < 0.001). Conclusion Bleeding patterns, endometrial thickness, ovarian activity, and endometrial histology among Egyptian users of LAPCs differed significantly depending on the nature of the contraceptive. |
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Authors:
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Mohamed Laban; Magda Abd Alhamid; Eman A Ibrahim; Ali Elyan; Ahlam Ibrahim |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-10-31 |
Journal Detail:
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Title: The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception Volume: - ISSN: 1473-0782 ISO Abbreviation: Eur J Contracept Reprod Health Care Publication Date: 2012 Oct |
Date Detail:
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Created Date: 2012-11-1 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9712127 Medline TA: Eur J Contracept Reprod Health Care Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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* Department of Obstetrics & Gynaecology. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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