Document Detail


Endometrial histology and post-partum mares treated with progesterone and synthetic GnRH (AY-24,031).
MedLine Citation:
PMID:  383989     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Foal heat was significantly delayed in 15 Thoroughbred and Quarter-horse mares by 200 mg progesterone in oil from Days 5--14 post partum. Nine of these mares subsequently received daily i.v. injections of 2 mg of a synthetic GnRH preparation (AY-24,031) from Day 2 of the progesterone-delayed oestrus but this treatment did not significantly shorten oestrus or hasten ovulation. Uterine biopsies taken on Day 15 post partum from all the mares showed a mixed endometrial morphology having both oestrous and dioestrous characteristics. There was an increased proliferation of endometrial glands in these animals at the time of ovulation compared to control mares having a normal foal heat.
Authors:
A M Pope; D L Campbell; J P Davidson
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of reproduction and fertility. Supplement     Volume:  -     ISSN:  0449-3087     ISO Abbreviation:  J. Reprod. Fertil. Suppl.     Publication Date:  1979  
Date Detail:
Created Date:  1979-11-29     Completed Date:  1979-11-29     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0225652     Medline TA:  J Reprod Fertil Suppl     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  587-91     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Endometrium / cytology*,  drug effects
Estrus / drug effects
Female
Fertility / drug effects
Gonadotropin-Releasing Hormone / pharmacology*
Hormones / pharmacology
Horses / physiology*
Ovulation / drug effects
Postpartum Period / drug effects*
Pregnancy
Progesterone / pharmacology*
Uterus / microbiology
Chemical
Reg. No./Substance:
0/Hormones; 33515-09-2/Gonadotropin-Releasing Hormone; 57-83-0/Progesterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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