Document Detail


Endometrial extramedullary haemopoiesis.
MedLine Citation:
PMID:  7616362     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Four cases of endometrial extramedullary haemopoiesis are reported, all with associated haematological disease. The diagnoses of a myeloproliferative disorder and thalassaemia trait were made as a consequence of the histological observations and subsequent haematological investigations in two cases. The third case occurred in a patient with an established diagnosis of chronic myeloid leukaemia. The diagnosis of extramedullary haemopoiesis in the final case was made on autopsy material from a patient with multiple myeloma. The endometrium from five other women with known myelofibrosis was examined but extramedullary haemopoiesis was not found. Endometrium from 32 fetuses did not contain haemopoietic elements, excluding the likelihood of the endometrium being a common site for extramedullary haemopoiesis in development. Endometrial extramedullary haemopoiesis is an uncommon finding, but it is worthy of note, as it may herald the presence of an underlying haematological abnormality.
Authors:
T M Creagh; B J Bain; D J Evans; C D Reid; R H Young; A M Flanagan
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of pathology     Volume:  176     ISSN:  0022-3417     ISO Abbreviation:  J. Pathol.     Publication Date:  1995 May 
Date Detail:
Created Date:  1995-08-18     Completed Date:  1995-08-18     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0204634     Medline TA:  J Pathol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  99-104     Citation Subset:  IM    
Affiliation:
Department of Histopathology, St. Mary's Hospital Medical School, Imperial College of Science, Technology and Medicine, London, U.K.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Endometrium / pathology,  physiopathology*
Female
Hematologic Diseases / pathology,  physiopathology*
Hematopoiesis, Extramedullary*
Humans
Leukemia, Myelogenous, Chronic, BCR-ABL Positive / physiopathology
Middle Aged
Multiple Myeloma / physiopathology
Myeloproliferative Disorders / physiopathology
alpha-Thalassemia / physiopathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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